Design and engineering of bispecific antibodies: insights and practical considerations
Bispecific antibodies (bsAbs) have attracted significant attention due to their dual binding
activity, which permits simultaneous targeting of antigens and synergistic binding effects …
activity, which permits simultaneous targeting of antigens and synergistic binding effects …
Structure and Dynamics Guiding Design of Antibody Therapeutics and Vaccines
Antibodies and other new antibody-like formats have emerged as one of the most rapidly
growing classes of biotherapeutic proteins. Understanding the structural features that drive …
growing classes of biotherapeutic proteins. Understanding the structural features that drive …
Hybrid Mass Spectrometry Applied across the Production of Antibody Biotherapeutics
E Christofi, M O'Hanlon, R Curtis… - Journal of the …, 2024 - ACS Publications
Post expression from the host cells, biotherapeutics undergo downstream processing steps
before final formulation. Mass spectrometry and biophysical characterization methods are …
before final formulation. Mass spectrometry and biophysical characterization methods are …