The current state of peritoneal dialysis

R Mehrotra, O Devuyst, SJ Davies… - Journal of the American …, 2016 - journals.lww.com
Technical innovations in peritoneal dialysis (PD), now used widely for the long-term
treatment of ESRD, have significantly reduced therapy-related complications, allowing …

Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: pathologic significance and potential therapeutic interventions

LS Aroeira, A Aguilera… - Journal of the …, 2007 - journals.lww.com
Peritoneal dialysis (PD) is a form of renal replacement and is based on the use of the
peritoneum as a semipermeable membrane across which ultrafiltration and diffusion take …

[HTML][HTML] AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis

J Morelle, C Marechal, Z Yu, H Debaix… - … England Journal of …, 2021 - Mass Medical Soc
Background Variability in ultrafiltration influences prescriptions and outcomes in patients
with kidney failure who are treated with peritoneal dialysis. Variants in AQP1, the gene that …

ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults: classification, measurement, interpretation and rationale for intervention

J Morelle, J Stachowska-Pietka… - Peritoneal Dialysis …, 2021 - journals.sagepub.com
Lay summary Peritoneal dialysis (PD) uses the peritoneal membrane for dialysis. The
peritoneal membrane is a thin layer of tissue that lines the abdomen. The lining is used as a …

Independent effects of systemic and peritoneal inflammation on peritoneal dialysis survival

M Lambie, J Chess, KL Donovan, YL Kim… - Journal of the …, 2013 - journals.lww.com
Systemic inflammation, as evidenced by elevated inflammatory cytokines, is a feature of
advanced renal failure and predicts worse survival. Dialysate IL-6 concentrations associate …

[HTML][HTML] Encapsulating peritoneal sclerosis: pathophysiology and current treatment options

RM Jagirdar, A Bozikas, SG Zarogiannis… - International journal of …, 2019 - mdpi.com
Encapsulating peritoneal sclerosis (EPS) is a life-threatening complication of long-term
peritoneal dialysis (PD), which may even occur after patients have switched to hemodialysis …

Early diagnostic markers for encapsulating peritoneal sclerosis: a case-control study

DE Sampimon, MR Korte, DL Barreto… - Peritoneal dialysis …, 2010 - journals.sagepub.com
Objective Encapsulating peritoneal sclerosis (EPS) is a severe complication of long-term
peritoneal dialysis (PD). The aim of this study was to investigate whether dialysate levels of …

Association of IL-6 and a functional polymorphism in the IL-6 gene with cardiovascular events in patients with CKD

B Spoto, F Mattace-Raso, E Sijbrands… - Clinical Journal of the …, 2015 - journals.lww.com
Results In adjusted analyses, serum IL-6 above the median value was associated with
history of CVD (P< 0.001) and predicted the incidence rate of CV events (hazard ratio, 1.66; …

A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving …

R Mehrotra, IB Stanaway, GP Jarvik, M Lambie… - Kidney international, 2021 - Elsevier
Movement of solutes across the peritoneum allows for the use of peritoneal dialysis to treat
kidney failure. However, there is a large inter-individual variability in the peritoneal solute …

Determinants of peritoneal membrane function over time

SJ Davies, L Mushahar, Z Yu, M Lambie - Seminars in nephrology, 2011 - Elsevier
Changes to peritoneal membrane function over time result in the development of
ultrafiltration failure in a proportion of PD patients and pose a risk for the rarer condition of …