Mechanobiology emerges at the crossroads of medicine, biology, biophysics and
engineering and describes how the responses of proteins, cells, tissues and organs to …

A current challenge in the life sciences is to understand how biological systems change their
structural, biophysical and chemical properties to adjust functionality. Addressing this issue …

Atomic force microscopy (AFM)-based methods have matured into a powerful nanoscopic
platform, enabling the characterization of a wide range of biological and synthetic …

The rapidly growing field of mechanobiology demands for robust and reproducible
characterization of cell mechanical properties. Recent achievements in understanding the …

A current challenge in the life sciences is to understand how the properties of individual
molecular machines adjust in order to meet the functional requirements of the cell. Recent …

Cells are constantly exposed to mechanical stimuli in their environment and have several
evolved mechanisms to sense and respond to these cues. It is becoming increasingly …

Genetic engineering by viral infection of single cells is useful to study complex systems such
as the brain. However, available methods for infecting single cells have drawbacks that limit …

The interactions between biomolecules and material interfaces at the molecular level are
complicated but very important for the development of materials science, nanotechnology …

Double-stranded (ds) RNA mediates the suppression of specific gene expression, it is the
genetic material of a number of viruses, and a key activator of the innate immune response …

A virus binding to a surface causes stress of the virus cage near the contact area. Here, we
investigate the potential role of substrate-induced structural perturbation in the mechanical …