The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …
DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
Sepsis-associated brain injury: underlying mechanisms and potential therapeutic strategies for acute and long-term cognitive impairments
N Sekino, M Selim, A Shehadah - Journal of Neuroinflammation, 2022 - Springer
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis causes cerebral dysfunction in the short and long term and induces …
infection. Sepsis causes cerebral dysfunction in the short and long term and induces …
Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression
Platelets have a wide range of functions including critical roles in hemostasis, thrombosis,
and immunity. We hypothesized that during acute inflammation, such as in life-threatening …
and immunity. We hypothesized that during acute inflammation, such as in life-threatening …
During sepsis and COVID-19, the pro-inflammatory and anti-inflammatory responses are concomitant
JM Cavaillon - Clinical Reviews in Allergy & Immunology, 2023 - Springer
The most severe forms of COVID-19 share many features with bacterial sepsis and have
thus been considered to be a viral sepsis. Innate immunity and inflammation are closely …
thus been considered to be a viral sepsis. Innate immunity and inflammation are closely …
Tissue-specific reprogramming of glutamine metabolism maintains tolerance to sepsis
Reprogramming metabolism is of great therapeutic interest for reducing morbidity and
mortality during sepsis-induced critical illness. Disappointing results from randomized …
mortality during sepsis-induced critical illness. Disappointing results from randomized …
Neurological complications of sepsis
Neurological complications of sepsis : Current Opinion in Critical Care Neurological
complications of sepsis : Current Opinion in Critical Care Log in or Register Subscribe to …
complications of sepsis : Current Opinion in Critical Care Log in or Register Subscribe to …
Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production
Staphylococcus aureus is a foremost bacterial pathogen responsible for a vast array of
human diseases. Staphylococcal superantigens (SAgs) constitute a family of exotoxins from …
human diseases. Staphylococcal superantigens (SAgs) constitute a family of exotoxins from …
Understanding post-sepsis syndrome: how can clinicians help?
EC Van der Slikke, LFE Beumeler… - Infection and Drug …, 2023 - Taylor & Francis
Sepsis is a global health challenge, with over 49 million cases annually. Recent medical
advancements have increased in-hospital survival rates to approximately 80%, but the …
advancements have increased in-hospital survival rates to approximately 80%, but the …
Polarization of microglia and its therapeutic potential in sepsis
LVG Castro, CF Gonçalves-de-Albuquerque… - International Journal of …, 2022 - mdpi.com
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection, leaving the inflammation process without a proper resolution, leading to tissue …
infection, leaving the inflammation process without a proper resolution, leading to tissue …
Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing
T Manabe, I Rácz, S Schwartz, L Oberle… - Journal of …, 2021 - Wiley Online Library
Sepsis‐associated encephalopathy (SAE) represents diverse cerebral dysfunctions in
response to pathogen‐induced systemic inflammation. Peripheral exposure to …
response to pathogen‐induced systemic inflammation. Peripheral exposure to …