Anogenital distance as a marker of androgen exposure in humans

A Thankamony, V Pasterski, KK Ong, CL Acerini… - …, 2016 - Wiley Online Library
Abnormal foetal testis development has been proposed to underlie common disorders of the
male reproductive system such as cryptorchidism, hypospadias, reduced semen quality and …

Anogenital distance or digit length ratio as measures of fetal androgen exposure: relationship to male reproductive development and its disorders

A Dean, RM Sharpe - The Journal of Clinical Endocrinology & …, 2013 - academic.oup.com
Context: Male reproductive disorders evident at birth or in young adulthood are remarkably
common. They are hypothesized to comprise a testicular dysgenesis syndrome (TDS), with a …

First trimester phthalate exposure and anogenital distance in newborns

SH Swan, S Sathyanarayana, ES Barrett… - Human …, 2015 - academic.oup.com
STUDY QUESTION Is first trimester phthalate exposure associated with anogenital distance
(AGD), a biomarker of prenatal androgen exposure, in newborns? SUMMARY ANSWER …

Anogenital distance in newborn daughters of women with polycystic ovary syndrome indicates fetal testosterone exposure

ES Barrett, KM Hoeger, S Sathyanarayana… - … origins of health and …, 2018 - cambridge.org
Polycystic ovary syndrome (PCOS) affects~ 7% of reproductive age women. Although its
etiology is unknown, in animals, excess prenatal testosterone (T) exposure induces PCOS …

Endometriosis and polycystic ovary syndrome are diametric disorders

NL Dinsdale, BJ Crespi - Evolutionary applications, 2021 - Wiley Online Library
Evolutionary and comparative approaches can yield novel insights into human adaptation
and disease. Endometriosis and polycystic ovary syndrome (PCOS) each affect up to 10% of …

Hypothetical roadmap towards endometriosis: prenatal endocrine-disrupting chemical pollutant exposure, anogenital distance, gut-genital microbiota and subclinical …

P García-Peñarrubia, AJ Ruiz-Alcaraz… - Human …, 2020 - academic.oup.com
BACKGROUND Endometriosis is a gynaecological hormone-dependent disorder that is
defined by histological lesions generated by the growth of endometrial-like tissue out of the …

Scientific Opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2015 - Wiley Online Library
This opinion describes the assessment of the risks to public health associated with
bisphenol A (BPA) exposure. Exposure was assessed for various groups of the human …

Polycystic ovary syndrome is associated with anogenital distance, a marker of prenatal androgen exposure

Y Wu, G Zhong, S Chen, C Zheng, D Liao… - Human …, 2017 - academic.oup.com
STUDY QUESTION Is the presence of polycystic ovary syndrome (PCOS) associated with
anogenital distance (AGD), a biomarker for the prenatal hormonal environment? SUMMARY …

Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother–child pairs

DV Lind, KM Main, HB Kyhl, DM Kristensen… - Human …, 2017 - academic.oup.com
STUDY QUESTION Is maternal use of mild analgesics in pregnancy associated with
anogenital distance (AGD)—the distance from the anus to the genitals—in the offspring …

Exposure to ambient particulate matter during specific gestational periods produces adverse obstetric consequences in mice

JL Blum, LC Chen, JT Zelikoff - Environmental Health …, 2017 - ehp.niehs.nih.gov
Background: Epidemiological studies associate inhalation of fine-sized particulate matter
(PM 2.5) during pregnancy with preterm birth (PTB) and low birth weight (LBW) but disagree …