Due to its specificity, fluorescence microscopy has become a quintessential imaging tool in
cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit …

Conventional approaches in drug development involve testing on 2D-cultured mammalian
cells, followed by experiments in rodents. Although this is the common strategy, it has …

Organoids, which are multicellular clusters with similar physiological functions to living
organs, have gained increasing attention in bioengineering. As organoids become more …

Scaffolds for tissue engineering aim to mimic the native extracellular matrix (ECM) that
provides physical support and biochemical signals to modulate multiple cell behaviors …

Liver diseases, characterized by high morbidity and mortality, represent a substantial
medical problem globally. The current therapeutic approaches are mainly aimed at reducing …

The decellularised extracellular matrix (dECM) of in vitro cell culture is a naturally derived
biomaterial formed by the removal of cellular components. The compositions of molecules in …

Decades of research have shown that two-dimensional cell culture studies are insufficient
for preclinical cancer diagnosis and treatment, and that cancer cells in three-dimensional …

目的对细胞来源脱细胞外基质(cell derived decellularized extracellular matrix, CDM)
在组织工程中的应用进展进行综述. 方法广泛查阅CDM 在组织工程中应用的相关文献 …

It is encouraging that cancer mortality rates continue to decline. However, almost 40% of
men and women will be diagnosed with cancer at some point during their lifetimes and …

Engineered cell clusters with similar cellular organization and physiological function to
tissues and organs of living organisms, also known as “organoids,” have been gaining more …