Disruption of the complex network that regulates redox homeostasis often underlies resistant
phenotypes, which hinder effective and long-lasting cancer eradication. In addition, the RNA …

Lichen natural products are a tremendous source of new bioactive chemical entities for drug
discovery. The ability to survive in harsh conditions can be directly correlated with the …

Lichen metabolites represent a wide range of substances with a variety of biological effects.
The present study was designed to analyze the potential antiproliferative, antimicrobial and …

Lichens are a source of various biologically active compounds. However, the knowledge
about them is still scarce, and their use in medicine is limited. This study aimed to investigate …

Evernia prunastri is a lichen widely distributed in the Northern Hemisphere. Its biological
properties still need to be discovered. Therefore, our paper focuses on studies of E. prunastri …

Background: Glioblastoma (GBM) is the most frequently occurring primary malignant central
nervous system tumor, with a poor prognosis and median survival below two years …

The Wnt/β-catenin, EGFR, and PI3K pathways frequently undergo upregulation in head and
neck squamous carcinoma (HNSCC) cells. Moreover, the Wnt/β-catenin pathway together …

Simple Summary Libertellenone T (B) is a natural product derived from the secondary
metabolites of the endolichenic fungus, Pseudoplectania sp. In this study, we investigated …

Cancer, while a multifactorial chronic disease with an increasing prevalence, has been the
subject of intense investigation, not only because of the growing need to find the main …

The pathophysiology of the severe course of COVID-19 is multifactorial and not entirely
elucidated. However, it is well known that the hyperinflammatory response and cytokine …