Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview

P Thangavel, D Park, YC Lee - International journal of environmental …, 2022 - mdpi.com
Several epidemiologic and toxicological studies have commonly viewed ambient fine
particulate matter (PM2. 5), defined as particles having an aerodynamic diameter of less …

Particulate matter air pollution: effects on the cardiovascular system

RB Hamanaka, GM Mutlu - Frontiers in endocrinology, 2018 - frontiersin.org
Air pollution is a complex mixture of gaseous and particulate components, each of which has
detrimental effects on human health. While the composition of air pollution varies greatly …

Effects of air pollution on human health–mechanistic evidence suggested by in vitro and in vivo modelling

H Chen, BG Oliver, A Pant, A Olivera, P Poronnik… - Environmental …, 2022 - Elsevier
Airborne particulate matter (PM) comprises both solid and liquid particles, including carbon,
sulphates, nitrate, and toxic heavy metals, which can induce oxidative stress and …

[HTML][HTML] The pathophysiological and molecular mechanisms of atmospheric PM2. 5 affecting cardiovascular health: A review

S Feng, F Huang, Y Zhang, Y Feng, Y Zhang… - Ecotoxicology and …, 2023 - Elsevier
Background Exposure to ambient fine particulate matter (PM 2.5, with aerodynamic diameter
less than 2.5 µm) is a leading environmental risk factor for global cardiovascular health …

[HTML][HTML] The impact of particulate matters on apoptosis in various organs: mechanistic and therapeutic perspectives

SM Aghaei-Zarch, AHS Nia, M Nouri… - Biomedicine & …, 2023 - Elsevier
Ecological air contamination is the non-homogenous suspension of insoluble particles into
gas or/and liquid fluids known as particulate matter (PM). It has been discovered that …

Adverse outcome pathway of fine particulate matter leading to increased cardiovascular morbidity and mortality: an integrated perspective from toxicology and …

Y Yu, Q Sun, T Li, X Ren, L Lin, M Sun, J Duan… - Journal of hazardous …, 2022 - Elsevier
Abstract Fine particulate matter (PM 2.5) exposure is a major threat to public health, and is
listed as one of the leading factors associated with global premature mortality. Among the …

Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2. 5 induced cardiac fibrosis

H Hu, L Li, H Zhang, Y Zhang, Q Liu, M Chen, J Ning… - Chemosphere, 2023 - Elsevier
Epidemiological studies have demonstrated strong associations between exposure to
ambient fine particulate matter (PM2. 5) and cardiac disease. To investigate the potential …

[HTML][HTML] PM2. 5-related cell death patterns

Y Wang, Y Zhong, J Liao, G Wang - International Journal of …, 2021 - ncbi.nlm.nih.gov
With the increasingly serious problem of environmental pollution, the health problems
caused by PM2. 5 are gradually coming into our line of sight. Previous researches have …

PM2. 5 triggered apoptosis in lung epithelial cells through the mitochondrial apoptotic way mediated by a ROS-DRP1-mitochondrial fission axis

X Liu, X Zhao, X Li, S Lv, R Ma, Y Qi… - Journal of hazardous …, 2020 - Elsevier
Epidemiological studies revealed a sharp increase in respiratory diseases attributed to PM
2.5. However, the underlying mechanisms remain unclear. Evidence suggested …

Arachidonic acid in follicular fluid of PCOS induces oxidative stress in a human ovarian granulosa tumor cell line (KGN) and upregulates GDF15 expression as a …

Y Ma, L Zheng, Y Wang, Y Gao, Y Xu - Frontiers in Endocrinology, 2022 - frontiersin.org
Polycystic ovarian ovary syndrome (PCOS) is the main cause of ovulatory infertility and a
common reproductive endocrine disease of women in reproductive age. In addition, nearly …