[HTML][HTML] Current developments and challenges of mRNA vaccines

J Chen, J Chen, Q Xu - Annual Review of Biomedical …, 2022 - annualreviews.org
mRNA vaccines have brought about a great revolution in the vaccine fields owing to their
simplicity and adaptability in antigen design, potential to induce both humoral and cell …

Waning immune humoral response to BNT162b2 Covid-19 vaccine over 6 months

EG Levin, Y Lustig, C Cohen, R Fluss… - … England Journal of …, 2021 - Mass Medical Soc
Background Despite high vaccine coverage and effectiveness, the incidence of symptomatic
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

[HTML][HTML] Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients

C Bergamaschi, E Terpos, M Rosati, M Angel, J Bear… - Cell reports, 2021 - cell.com
Early responses to vaccination are important for shaping both humoral and cellular
protective immunity. Dissecting innate vaccine signatures may predict immunogenicity to …

Booster vaccination strategy: Necessity, immunization objectives, immunization strategy, and safety

H Meng, J Mao, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
At present, the global COVID‐19 epidemic has not been completely controlled, and
epidemic prevention and control still face severe challenges. As there is no specific …

[HTML][HTML] The neutralizing antibody response post COVID-19 vaccination in patients with myeloma is highly dependent on the type of anti-myeloma treatment

E Terpos, M Gavriatopoulou… - Blood Cancer …, 2021 - nature.com
Recent data suggest a suboptimal antibody response to COVID-19 vaccination in patients
with hematological malignancies. Neutralizing antibodies (NAbs) against SARS-CoV-2 were …

[HTML][HTML] Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

L Renia, YS Goh, A Rouers, N Le Bert, WN Chia… - Nature …, 2022 - nature.com
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …

[HTML][HTML] Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines

J Wei, KB Pouwels, N Stoesser, PC Matthews… - Nature Medicine, 2022 - nature.com
Antibody responses are an important part of immunity after Coronavirus Disease 2019
(COVID-19) vaccination. However, antibody trajectories and the associated duration of …

[HTML][HTML] Antibody responses to BNT162b2 mRNA COVID-19 vaccine and their predictors among healthcare workers in a tertiary referral hospital in Japan

T Kageyama, K Ikeda, S Tanaka, T Taniguchi… - Clinical Microbiology …, 2021 - Elsevier
Objectives This study aimed to determine antibody responses in healthcare workers who
receive the BNT162b2 mRNA COVID-19 vaccine and identify factors that predict the …

[HTML][HTML] Evaluation of anti-SARS-Cov-2 S-RBD IgG antibodies after COVID-19 mRNA BNT162b2 vaccine

B Lo Sasso, RV Giglio, M Vidali, C Scazzone, G Bivona… - Diagnostics, 2021 - mdpi.com
(1) Background: The evaluation of anti-spike protein receptor-binding domain (S-RBD)
antibodies represents a useful tool to estimate the individual protection against Severe …

[HTML][HTML] Neutralizing antibodies in COVID-19 patients and vaccine recipients after two doses of BNT162b2

J Favresse, C Gillot, L Di Chiaro, C Eucher, M Elsen… - Viruses, 2021 - mdpi.com
The evaluation of the neutralizing capacity of anti-SARS-CoV-2 antibodies is important
because they represent real protective immunity. In this study we aimed to measure and …