Aldehydes are carbonyl compounds found ubiquitously in the environment, derived from
both natural and anthropogenic sources. As the aldehydes are reactive species, therefore …

Retinoic acid (RA) is the active metabolite of vitamin A (retinol) that controls growth and
development. The first step of RA synthesis is controlled by enzymes of the alcohol …

Retinoic acid (RA), the most active retinoid, is synthesized in two steps from retinol. The first
step, oxidation of retinol to retinaldehyde, is catalyzed by cytosolic alcohol dehydrogenases …

Abstract According to International Agency for Research on Cancer, ethanol and
acetaldehyde belong to group 1 of human carcinogens. The accurate mechanism by which …

Objective. To offer new prognostic evaluations by exploring potentially distinctive genetic
features of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) …

BACKGROUND: Episkin™ and full thickness model from Episkin™(FTM) are human skin
models obtained from in vitro growth of keratinocytes into the five typical layers of the …

Mammalian alcohol dehydrogenase (ADH) can be divided into six classes, ADH1–ADH6,
according to primary structure and function, where the classes are further subdivided into …

In western countries, alcohol consumption is widespread in women of reproductive age, and
in binge quantities. These countries also continue to have high incidences of unplanned …

Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and
toxicokinetics in a comprehensible, interrelated, and applied manner. It integrates the …

Background: Increased alcohol consumption has been associated with depression and
alcoholism, but whether these associations are causal remains unclear. We tested whether …