A brief review on solid lipid nanoparticles: Part and parcel of contemporary drug delivery systems

Y Duan, A Dhar, C Patel, M Khimani, S Neogi… - RSC …, 2020 - pubs.rsc.org
Drug delivery technology has a wide spectrum, which is continuously being upgraded at a
stupendous speed. Different fabricated nanoparticles and drugs possessing low solubility …

SLN and NLC for topical, dermal, and transdermal drug delivery

EB Souto, I Baldim, WP Oliveira, R Rao… - Expert opinion on …, 2020 - Taylor & Francis
Introduction From a biopharmaceutical standpoint, the skin is recognized as an interesting
route for drug delivery. In general, small molecules are able to penetrate the stratum …

Solid lipid nanoparticles and nanostructured lipid carriers: A review of the methods of manufacture and routes of administration

J Akbari, M Saeedi, F Ahmadi… - Pharmaceutical …, 2022 - Taylor & Francis
The bioavailability of drugs is dependent on several factors such as solubility and the
administration route. A drug with poor aqueous solubility, therefore, poses challenges with …

Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: Applications, advantages and disadvantages

P Ghasemiyeh… - Research in …, 2018 - journals.lww.com
During the recent years, more attentions have been focused on lipid base drug delivery
system to overcome some limitations of conventional formulations. Among these delivery …

Formulations based on solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for cutaneous use: A review

A Garcês, MH Amaral, JMS Lobo, AC Silva - European Journal of …, 2018 - Elsevier
Cutaneous use of lipid nanoparticles (solid lipid nanoparticles, SLN and nanostructured lipid
carriers, NLC) has been showing promising results. These systems consist of low viscosity …

Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

Functional nano-systems for transdermal drug delivery and skin therapy

L Liu, W Zhao, Q Ma, Y Gao, W Wang, X Zhang… - Nanoscale …, 2023 - pubs.rsc.org
Transdermal drug delivery is one of the least intrusive and patient-friendly ways for
therapeutic agent administration. Recently, functional nano-systems have been …

Dissolving microneedle patches loaded with amphotericin B microparticles for localised and sustained intradermal delivery: Potential for enhanced treatment of …

K Peng, LK Vora, IA Tekko, AD Permana… - Journal of Controlled …, 2021 - Elsevier
Fungal infections affect millions of people globally and are often unreceptive to conventional
topical or oral preparations because of low drug bioavailability at the infection site, lack of …

Transferosomes as a transdermal drug delivery system: Dermal kinetics and recent developments

N Matharoo, H Mohd… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
The development of innovative approaches to deliver medications has been growing now
for the last few decades and generates a growing interest in the dermatopharmaceutical …

Preclinical safety of solid lipid nanoparticles and nanostructured lipid carriers: Current evidence from in vitro and in vivo evaluation

S Doktorovova, AB Kovačević, ML Garcia… - European Journal of …, 2016 - Elsevier
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were designed as
exceptionally safe colloidal carriers for the delivery of poorly soluble drugs. SLN/NLC have …