Cryptococcus: from environmental saprophyte to global pathogen

RC May, NRH Stone, DL Wiesner, T Bicanic… - Nature Reviews …, 2016 - nature.com
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis

KJ Kwon-Chung, JA Fraser… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

Basic principles of the virulence of Cryptococcus

O Zaragoza - Virulence, 2019 - Taylor & Francis
Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Cryptococcal Disease in Diverse Hosts

DB Meya, PR Williamson - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points Cryptococcal Disease in Diverse Hosts Worldwide, cryptococcal meningitis kills
up to 180,000 persons annually and is the most common cause of nonviral meningitis in the …

Immune Response of Galleria mellonella against Human Fungal Pathogens

N Trevijano-Contador, O Zaragoza - Journal of Fungi, 2018 - mdpi.com
In many aspects, the immune response against pathogens in insects is similar to the innate
immunity in mammals. This has caused a strong interest in the scientific community for the …

Cryptococcus neoformans: historical curiosity to modern pathogen

D Srikanta, FH Santiago‐Tirado, TL Doering - Yeast, 2014 - Wiley Online Library
The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Cryptococcal pathogenic mechanisms: a dangerous trip from the environment to the brain

SK Esher, O Zaragoza, JA Alspaugh - Memorias do Instituto Oswaldo …, 2018 - SciELO Brasil
Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious
infections, most commonly of the central nervous system (CNS). C. neoformans is mainly …

Immunology of cryptococcal infections: developing a rational approach to patient therapy

W Elsegeiny, KA Marr, PR Williamson - Frontiers in immunology, 2018 - frontiersin.org
Cryptococcal meningoencephalitis is responsible for upwards of 15% of HIV-related deaths
worldwide and is currently the most common cause of non-viral meningitis in the US …

A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus …

C Probst, M Hallas-Møller, JØ Ipsen, JT Brooks… - PLOS …, 2023 - journals.plos.org
Fungi often adapt to environmental stress by altering their size, shape, or rate of cell division.
These morphological changes require reorganization of the cell wall, a structural feature …

Crossover fungal pathogens: the biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans

GM Gauthier, NP Keller - Fungal genetics and biology, 2013 - Elsevier
The outbreak of fungal meningitis associated with contaminated methylprednisolone acetate
has thrust the importance of fungal infections into the public consciousness. The …