New concepts for an old problem: the diagnosis of endometrial hyperplasia

PA Sanderson, HOD Critchley… - Human reproduction …, 2017 - academic.oup.com
BACKGROUND Endometrial hyperplasia (EH) is a uterine pathology representing a
spectrum of morphological endometrial alterations. It is predominantly characterized by an …

Molecular genetics of endometrial carcinoma

DW Bell, LH Ellenson - Annual Review of Pathology …, 2019 - annualreviews.org
Endometrial cancer is the most commonly diagnosed gynecologic malignancy in the United
States. Endometrioid endometrial carcinomas constitute approximately 85% of newly …

[PDF][PDF] ESGO/ESHRE/ESGE Guidelines for the fertility-sparing treatment of patients with endometrial carcinoma,

A Rodolakis, G Scambia, F Planchamp… - Human …, 2023 - academic.oup.com
STUDY QUESTION How should fertility-sparing treatment of patients with endometrial
carcinoma be performed? SUMMARY ANSWER Forty-eight recommendations were …

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

GL Mutter, MC Lin, JT Fitzgerald, JB Kum… - Journal of the …, 2000 - academic.oup.com
Background: PTEN tumor suppressor gene mutations are the most frequent genetic lesions
in endometrial adenocarcinomas of the endometrioid subtype. Testing the hypothesis that …

Concurrent endometrial carcinoma in women with a biopsy diagnosis of atypical endometrial hyperplasia: a Gynecologic Oncology Group study

CL Trimble, J Kauderer, R Zaino, S Silverberg… - Cancer, 2006 - Wiley Online Library
BACKGROUND Adenocarcinoma of the endometrium is the most common gynecologic
malignancy in the United States, accounting for approximately 36,000 diagnoses of invasive …

Incidence of endometrial hyperplasia

SD Reed, KM Newton, WL Clinton, M Epplein… - American journal of …, 2009 - Elsevier
OBJECTIVE: The objective of the study was to estimate the age-specific incidence of
endometrial hyperplasia: simple, complex, and atypical, in order of increasing likelihood of …

Management of endometrial precancers

CL Trimble, M Leitao, K Lu, O Ioffe… - Obstetrics & …, 2012 - journals.lww.com
Abstract In the United States, endometrial cancer is the most commonly diagnosed cancer of
the female reproductive system. Strategies to sensitively and accurately diagnose …

Endometrial intraepithelial neoplasia (EIN): will it bring order to chaos?

GL Mutter - Gynecologic oncology, 2000 - gynecologiconcology-online.net
The diagnosis of precancerous lesions of the endometrium remains unstandardized
because existing World Health Organization classification categories do not correspond to …

Observer variation of encapsulated follicular lesions of the thyroid gland

M Hirokawa, JA Carney, JR Goellner… - The American journal …, 2002 - journals.lww.com
Although histologic definition of follicular thyroid lesions is readily available, application of
the diagnostic criteria and personal experience may lead to disagreement among …

Reproducibility of the diagnosis of atypical endometrial hyperplasia: a Gynecologic Oncology Group study

RJ Zaino, J Kauderer, CL Trimble, SG Silverberg… - Cancer, 2006 - Wiley Online Library
BACKGROUND Most gynecologists determine therapy based on current International
Society of Gynecologic Pathologists (ISGP)/World Health Organization classification of …