Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …

Hepatic steatosis is an underlying feature of nonalcoholic fatty liver disease (NAFLD), which
is the most common form of liver disease and is present in up to∼ 70% of individuals who …

Background & Aims Non-alcoholic steatohepatitis (NASH) is associated with the
dysregulation of lipid metabolism and hepatic inflammation, though the underlying …

Homeostasis of energy is regulated by genetic factors, food intake, and energy expenditure.
When energy input is greater than expenditure, the balance is positive, which can lead to …

Insulin resistance and muscle mass loss often coincide in individuals with type 2 diabetes.
Most patients with type 2 diabetes are overweight, and it is well established that obesity and …

Adropin is a novel 76-amino acid-peptide that is expressed in different tissues and cells
including the liver, pancreas, heart and vascular tissues, kidney, milk, serum, plasma and …

Adropin is a secreted peptide that improves hepatic steatosis and glucose homeostasis
when administered to diet‐induced obese mice. It is not clear if adropin is a peptide …

Lipid overload results in lipid redistribution among metabolic organs such as liver, adipose,
and muscle; therefore, the interplay between liver and other organs is important to maintain …

Liver steatosis is associated with the development of insulin resistance and the
pathogenesis of type 2 diabetes. We tested the hypothesis that protein signals originating …