No matter what their origin, strain and family, viruses have evolved exquisite strategies to
reach and penetrate specific target cells where they hijack the cellular machinery to express …

Naegleria fowleri, a thermophilic flagellate amoeba known as a “brain‐eating” amoeba, is
the aetiological agent of a perilous and devastating waterborne disease known as primary …

The CRISPR/Cas9 systems have revolutionized the field of genome editing by providing
unprecedented control over gene sequences and gene expression in many species …

The global vaccine market is diverse while facing a plethora of novel developments. Genetic
modification (GM) techniques facilitate the design of'smarter'vaccines. For many of the major …

Given the limitations of conventional invasive vaccines, such as the requirement for a cold
chain system and trained personnel, needle-based injuries, and limited immunogenicity …

Recombinant native-like HIV-1 envelope glycoprotein (Env) trimers are used in candidate
vaccines aimed at inducing broadly neutralizing antibodies. While state-of-the-art SOSIP or …

Integrase-defective lentiviral vectors (IDLVs) have been used as a safe and efficient delivery
system in several immunization protocols in murine and non-human primate preclinical …

Viral vectors represent an attractive technology for vaccine delivery. We exploited the
integrase defective lentiviral vector (IDLV) as a platform for delivering relevant antigens …

Several COVID-19 vaccine strategies utilizing new formulations for the induction of
neutralizing antibodies (nAbs) and T cell immunity are still under evaluation in preclinical …

Abstract Parainfluenza virus 5 (PIV5) is a negative‐sense, single‐stranded RNA virus that
can infect humans and many species of animals. Infection in these reservoir hosts is …