Ultrafast magic angle spinning solid-state NMR spectroscopy: Advances in methodology and applications
Solid-state NMR spectroscopy is one of the most commonly used techniques to study the
atomic-resolution structure and dynamics of various chemical, biological, material, and …
atomic-resolution structure and dynamics of various chemical, biological, material, and …
[HTML][HTML] Solid-state NMR spectroscopy in pharmaceutical sciences
Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials
in a non-disruptive and non-invasive manner. The obtained molecular properties at …
in a non-disruptive and non-invasive manner. The obtained molecular properties at …
NMR crystallography of molecular organics
P Hodgkinson - Progress in Nuclear Magnetic Resonance …, 2020 - Elsevier
Developments of NMR methodology to characterise the structures of molecular organic
structures are reviewed, concentrating on the previous decade of research in which density …
structures are reviewed, concentrating on the previous decade of research in which density …
Investigating miscibility and molecular mobility of nifedipine-PVP amorphous solid dispersions using solid-state NMR spectroscopy
Solid-state NMR (SSNMR) 1H T1 and T1ρ relaxation times were used to evaluate the
miscibility of amorphous solid dispersions of nifedipine (NIF) and polyvinylpyrrolidone (PVP) …
miscibility of amorphous solid dispersions of nifedipine (NIF) and polyvinylpyrrolidone (PVP) …
Fast magic-angle sample spinning solid-state NMR at 60–100 kHz for natural abundance samples
Y Nishiyama - Solid State Nuclear Magnetic Resonance, 2016 - Elsevier
In spite of tremendous progress made in pulse sequence designs and sophisticated
hardware developments, methods to improve sensitivity and resolution in solid-state NMR …
hardware developments, methods to improve sensitivity and resolution in solid-state NMR …
Dynamic nuclear polarization enhanced NMR spectroscopy for pharmaceutical formulations
AJ Rossini, CM Widdifield, A Zagdoun… - Journal of the …, 2014 - ACS Publications
Dynamic nuclear polarization (DNP) enhanced solid-state NMR spectroscopy at 9.4 T is
demonstrated for the detailed atomic-level characterization of commercial pharmaceutical …
demonstrated for the detailed atomic-level characterization of commercial pharmaceutical …
Structural and dynamic properties of amorphous solid dispersions: the role of solid-state nuclear magnetic resonance spectroscopy and relaxometry
A Paudel, M Geppi, G Van den Mooter - Journal of pharmaceutical …, 2014 - Elsevier
Amorphous solid dispersions (ASDs) are one of the frontier strategies to improve solubility
and dissolution rate of poorly soluble drugs and hence tackling the growing challenges in …
and dissolution rate of poorly soluble drugs and hence tackling the growing challenges in …
Interplay of structure and dynamics in functional macromolecular and supramolecular systems as revealed by magnetic resonance spectroscopy
MR Hansen, R Graf, HW Spiess - Chemical Reviews, 2016 - ACS Publications
The characterization of structure and dynamics of macromolecular and supramolecular
systems represents an ongoing challenge. This is due to the fact that soft matter systems …
systems represents an ongoing challenge. This is due to the fact that soft matter systems …
Molecular interactions in posaconazole amorphous solid dispersions from two-dimensional solid-state NMR spectroscopy
Molecular interactions between the active pharmaceutical ingredient and polymer have
potentially substantial impacts on the physical stability of amorphous solid dispersions …
potentially substantial impacts on the physical stability of amorphous solid dispersions …
Opportunities and Challenges in Applying Solid‐State NMR Spectroscopy in Organic Mechanochemistry
In recent years it is shown that mechanochemical strategies can be beneficial in directed
conversions of organic compounds. Finding new reactions proved difficult, and due to the …
conversions of organic compounds. Finding new reactions proved difficult, and due to the …