Rationally designed ruthenium complexes for breast cancer therapy
G Golbaghi, A Castonguay - Molecules, 2020 - mdpi.com
Since the discovery of the anticancer potential of ruthenium-based complexes, several
species were reported as promising candidates for the treatment of breast cancer, which …
species were reported as promising candidates for the treatment of breast cancer, which …
[HTML][HTML] Unlocking the potential of 1, 4-naphthoquinones: A comprehensive review of their anticancer properties
E Angulo-Elizari, A Henriquez-Figuereo… - European Journal of …, 2024 - Elsevier
Cancer encompasses a group of pathologies with common characteristics, high incidence,
and prevalence in all countries. Although there are treatments available for this disease …
and prevalence in all countries. Although there are treatments available for this disease …
Half sandwich Ru (II)-acylthiourea complexes: DNA/HSA-binding, anti-migration and cell death in a human breast tumor cell line
L Colina-Vegas, L Luna-Dulcey, AM Plutín… - Dalton …, 2017 - pubs.rsc.org
Organometallic ruthenium complexes as potential anticancer agents have been explored
due to their suitable properties, such as stability in the solid state and in solution, water …
due to their suitable properties, such as stability in the solid state and in solution, water …
Lapachol in the design of a new ruthenium (II)-diphosphine complex as a promising anticancer metallodrug
KM Oliveira, J Honorato, FC Demidoff… - Journal of Inorganic …, 2021 - Elsevier
The preparation of two new Ru (II)/diphosphine complexes containing Lapachol (Lap) and
Lawsone (Law):(1)[Ru (Lap)(dppm) 2] PF 6 and (2)[Ru (Law)(dppm) 2] PF 6, where dppm …
Lawsone (Law):(1)[Ru (Lap)(dppm) 2] PF 6 and (2)[Ru (Law)(dppm) 2] PF 6, where dppm …
Synthesis, characterization and anti-cancer studies of Mn (II), Cu (II), Zn (II) and Pt (II) dithiocarbamate complexes-crystal structures of the Cu (II) and Pt (II) complexes
Abstract Mn (II), Cu (II), Zn (II) and Pt (II) complexes of 2-((p-tolylamino) methyl)
phenolyldithiocarbamate were synthesized and characterized by elemental analyses and …
phenolyldithiocarbamate were synthesized and characterized by elemental analyses and …
New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway
AE Graminha, C Popolin, JH de Araujo-Neto… - European Journal of …, 2022 - Elsevier
In this work we present the synthesis and characterization of six new ruthenium compounds
with general formulae [Ru (L)(dppb)(bipy)] PF 6 and [Ru (L)(dppe) 2] PF 6 where L= salicylic …
with general formulae [Ru (L)(dppb)(bipy)] PF 6 and [Ru (L)(dppe) 2] PF 6 where L= salicylic …
Transport of the Ruthenium Complex [Ru(GA)(dppe)2]PF6 into Triple-Negative Breast Cancer Cells Is Facilitated by Transferrin Receptors
MA Naves, AE Graminha, LC Vegas… - Molecular …, 2019 - ACS Publications
The triple-negative breast cancer subtype (TNBC) is highly aggressive and metastatic and
corresponds to 15–20% of diagnosed cases. TNBC treatment is hampered, because these …
corresponds to 15–20% of diagnosed cases. TNBC treatment is hampered, because these …
Novel lawsone-containing ruthenium (II) complexes: Synthesis, characterization and anticancer activity on 2D and 3D spheroid models of prostate cancer cells
RA De Grandis, PWS Dos Santos, KM de Oliveira… - Bioorganic …, 2019 - Elsevier
This study describes a series of newly synthesized phosphine/diimine ruthenium complexes
containing the lawsone as bioligand with enhanced cytotoxicity against different cancer …
containing the lawsone as bioligand with enhanced cytotoxicity against different cancer …
Ru (II)-Naphthoquinone complexes with high selectivity for triple-negative breast cancer
KM Oliveira, EJ Peterson, MC Carroccia… - Dalton …, 2020 - pubs.rsc.org
Six new ruthenium (II) complexes with lapachol (Lap) and lawsone (Law) with the general
formula [Ru (L)(P–P)(bipy)] PF6, where L= Lap or Law, P–P= 1, 2′-bis (diphenylphosphino) …
formula [Ru (L)(P–P)(bipy)] PF6, where L= Lap or Law, P–P= 1, 2′-bis (diphenylphosphino) …
Selective Ru (II)/lawsone complexes inhibiting tumor cell growth by apoptosis
KM Oliveira, LD Liany, RS Corrêa, VM Deflon… - Journal of inorganic …, 2017 - Elsevier
New Ru (II) complexes with lawsone (law) characterized as trans-[Ru (law)(PPh 3) 2 (NN)]
PF 6, where PPh 3 means triphenylphosphine and NN is 2, 2′-bipyridine (1), 4, 4 …
PF 6, where PPh 3 means triphenylphosphine and NN is 2, 2′-bipyridine (1), 4, 4 …