Incidence and outcomes associated with Clostridium difficile infections: a systematic review and meta-analysis

AR Marra, EN Perencevich, RE Nelson… - JAMA Network …, 2020 - jamanetwork.com
Importance An understanding of the incidence and outcomes ofClostridium difficileinfection
(CDI) in the United States can inform investments in prevention and treatment interventions …

The Role of Bezlotoxumab for the Prevention of Recurrent Clostridioides difficile Infections: A Review of the Current Literature and Paradigm Shift after 2021

ML Hyte, LJ Arphai, CJ Vaughn, SH Durham - Antibiotics, 2022 - mdpi.com
Clostridioides difficile infections (CDIs), and particularly recurrent infections, cause a
significant burden on the health-care system. Bezlotoxumab is a new agent for the …

Clostridioides difficile epidemiology in the Middle and the Far East

M Brajerova, J Zikova, M Krutova - Anaerobe, 2022 - Elsevier
Objectives Clostridioides difficile is an important pathogen of healthcare-associated
gastrointestinal infections. Recently, an increased number of C. difficile infection (CDI) …

Proton pump inhibitor-induced gut dysbiosis increases mortality rates for patients with clostridioides difficile infection

CY Lin, HT Cheng, CJ Kuo, YS Lee… - Microbiology …, 2022 - Am Soc Microbiol
Clostridioides difficile infection (CDI) is associated with high mortality rates among patients
with chronic illnesses. We aimed to identify avoidable risk factors to reduce the mortality rate …

Mortality Following Clostridioides difficile Infection in Europe: A Retrospective Multicenter Case-Control Study

J Czepiel, M Krutova, A Mizrahi, N Khanafer, DA Enoch… - Antibiotics, 2021 - mdpi.com
We aimed to describe the clinical presentation, treatment, outcome and report on factors
associated with mortality over a 90-day period in Clostridioides difficile infection (CDI) …

The burden of Clostridioides difficile on COVID‐19 hospitalizations in the USA

A Sohal, H Chaudhry, P Singla… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Aim Clostridioides difficile infection (CDI) is the leading cause of
hospital acquired‐infectious diarrhea in the USA. In this study, we assess the prevalence …

Clostridioides difficile recurrence in individuals with and without cancer: a Swedish population-based cohort study

P Mpakaniye, A Boven, S Callens, L Engstrand… - Infection, 2024 - Springer
Purpose Patients with cancer are vulnerable to Clostridioides difficile infection (CDI) due to
their disease, treatment and regular hospital contact, yet if CDI-recurrence is more common …

[HTML][HTML] Risk of complications and mortality following recurrent and non-recurrent Clostridioides difficile infection: a retrospective observational database study in …

DA Enoch, T Murray-Thomas, N Adomakoh… - Journal of Hospital …, 2020 - Elsevier
Structured summary Background Clostridioides difficile infection (CDI) increases the risk of
complications and mortality. We assessed the magnitude of these outcomes in a large …

[HTML][HTML] Clostridioides difficile infection in cancer patients receiving immune checkpoint inhibitors

S Vasavada, K Panneerselvam, R Amin… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but
are associated with immune-mediated diarrhea and colitis (IMDC). Clostridioides difficile …

Clostridium difficile infection in oncology patients: epidemiology, pathophysiology, risk factors, diagnosis, and treatment

O Abughanimeh, A Qasrawi, O Kaddourah… - Hospital …, 2018 - Taylor & Francis
Clostridium difficile infection (CDI) is one of the most common healthcare-associated
infections in the United States. Its incidence has been increasing in the recent years despite …