Epigenetic regulation of aging: implications for interventions of aging and diseases

K Wang, H Liu, Q Hu, L Wang, J Liu, Z Zheng… - Signal transduction and …, 2022 - nature.com
Aging is accompanied by the decline of organismal functions and a series of prominent
hallmarks, including genetic and epigenetic alterations. These aging-associated epigenetic …

[HTML][HTML] Nutrition, longevity and disease: From molecular mechanisms to interventions

VD Longo, RM Anderson - Cell, 2022 - cell.com
Diet as a whole, encompassing food composition, calorie intake, and the length and
frequency of fasting periods, affects the time span in which health and functional capacity …

Dietary regulation in health and disease

Q Wu, ZJ Gao, X Yu, P Wang - Signal Transduction and Targeted …, 2022 - nature.com
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

[HTML][HTML] Dietary approaches for exploiting metabolic vulnerabilities in cancer

O Menyhárt, B Győrffy - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Renewed interest in tumor metabolism sparked an enthusiasm for dietary interventions to
prevent and treat cancer. Changes in diet impact circulating nutrient levels in the plasma …

Looking for the philosopher's stone: Emerging approaches to target the hallmarks of aging in the skin

JM Lemaitre - Journal of the European Academy of …, 2024 - Wiley Online Library
Senescence and epigenetic alterations are two important hallmarks of cellular aging. During
aging, cells subjected to stress undergo many cycles of damage and repair before finally …

Intermittent fasting as a dietary intervention with potential sexually dimorphic health benefits

J Rius-Bonet, S Macip, D Closa… - Nutrition …, 2025 - academic.oup.com
Intermittent fasting (IF) has proven to be a feasible dietary intervention for the wider
population. The recent increase in IF clinical trials highlights its potential effects on health …

Adipose tissue aging: An update on mechanisms and therapeutic strategies

Z Cai, B He - Metabolism, 2023 - Elsevier
Aging is a complex biological process characterized by a progressive loss of physiological
integrity and increased vulnerability to age-related diseases. Adipose tissue plays central …

Effects of obesity and calorie restriction on cancer development

E Sergeeva, T Ruksha, Y Fefelova - International Journal of Molecular …, 2023 - mdpi.com
The risk of malignant tumor development is increasing in the world. Obesity is an
established risk factor for various malignancies. There are many metabolic alterations …

Metabolic reprogramming by reduced calorie intake or pharmacological caloric restriction mimetics for improved cancer immunotherapy

E Eriau, J Paillet, G Kroemer, JG Pol - Cancers, 2021 - mdpi.com
Simple Summary Reduced food intake significantly enhances healthy lifespan in both model
animals and humans, and decreases the incidence of cancer and other age-related …

[HTML][HTML] Effects of Different Exercises Combined with Different Dietary Interventions on Body Composition: A Systematic Review and Network Meta-Analysis

Y Xie, Y Gu, Z Li, B He, L Zhang - Nutrients, 2024 - mdpi.com
Background: Exercise and dietary interventions are essential for maintaining weight and
reducing fat accumulation. With the growing popularity of various dietary strategies …