Inflammation is a natural reaction of the innate immune system that evolved primarily to
protect the human body from invading pathogens and to heal injuries. There are two …

Importance Children with developmental delays are at a heightened risk of experiencing
mental health challenges, and this risk is exacerbated among racially minoritized children …

Chronic inflammation is a hallmark of age-related disease states. The effectiveness of
inflammatory proteins including C-reactive protein (CRP) in assessing long-term …

Background DNA methylation levels at specific sites can be used to proxy C-reactive protein
(CRP) levels, providing a potentially more stable and accurate indicator of sustained …

GrimAge acceleration has previously predicted age-related morbidities and mortality. In the
current study, we sought to examine how GrimAge is associated with genetic predisposition …

Tobacco smoke exposure significantly increases the level of global nucleoside damage. To
evaluate all aspects of nucleic acid (NA) modifications, NA adductomics analyzes DNA, RNA …

Background Recent research reported that frailty was prevalent among adults with chronic
kidney disease (CKD) in clinical trials, and monocytes illustrated a similar difference in these …

Background Targeting effective strategies to prevent cognitive decline is key in the aging
population. Some diets have been linked to a slower cognitive decline, potentially through …

Frailty is classically associated with advanced age but is also an important predictor of
clinical outcomes in comparatively young adults with cirrhosis. We examined the association …

This study aims to investigate the expression differences of peripheral blood mononuclear
cells (PBMCs) in patients with elderly rheumatoid arthritis (ERA). Differentially expressed …