[HTML][HTML] A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome
After more than a century of active research, the notion that the human fetal environment is
sterile and that the neonate's microbiome is acquired during and after birth was an accepted …
sterile and that the neonate's microbiome is acquired during and after birth was an accepted …
Microbiomes as metacommunities: understanding host-associated microbes through metacommunity ecology
Interest in host-associated microbiomes has skyrocketed recently, yet our ability to explain
microbiome variation has remained stubbornly low. Considering scales of interaction …
microbiome variation has remained stubbornly low. Considering scales of interaction …
inStrain profiles population microdiversity from metagenomic data and sensitively detects shared microbial strains
Coexisting microbial cells of the same species often exhibit genetic variation that can affect
phenotypes ranging from nutrient preference to pathogenicity. Here we present inStrain, a …
phenotypes ranging from nutrient preference to pathogenicity. Here we present inStrain, a …
[HTML][HTML] Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites
D Bogaert, GJ Van Beveren, EM de Koff, PL Parga… - Cell Host & Microbe, 2023 - cell.com
Early-life microbiota seeding and subsequent development is crucial to future health.
Cesarean-section (CS) birth, as opposed to vaginal delivery, affects early mother-to-infant …
Cesarean-section (CS) birth, as opposed to vaginal delivery, affects early mother-to-infant …
Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth
Immediately after birth, newborn babies experience rapid colonization by microorganisms
from their mothers and the surrounding environment. Diseases in childhood and later in life …
from their mothers and the surrounding environment. Diseases in childhood and later in life …
[HTML][HTML] Mother-to-infant microbial transmission from different body sites shapes the developing infant gut microbiome
The acquisition and development of the infant microbiome are key to establishing a healthy
host-microbiome symbiosis. The maternal microbial reservoir is thought to play a crucial role …
host-microbiome symbiosis. The maternal microbial reservoir is thought to play a crucial role …
Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics
Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
Studying vertical microbiome transmission from mothers to infants by strain-level metagenomic profiling
The gut microbiome becomes shaped in the first days of life and continues to increase its
diversity during the first months. Links between the configuration of the infant gut microbiome …
diversity during the first months. Links between the configuration of the infant gut microbiome …
[HTML][HTML] Oral administration of maternal vaginal microbes at birth to restore gut microbiome development in infants born by caesarean section: A pilot randomised …
Background Birth by caesarean section (CS) is associated with aberrant gut microbiome
development and greater disease susceptibility later in life. We investigated whether oral …
development and greater disease susceptibility later in life. We investigated whether oral …
Do bacteria shape our development? Crosstalk between intestinal microbiota and HPA axis
C de Weerth - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
The human body contains as many bacteria in the intestine as the total number of human
body cells. These bacteria have a central position in human health and disease, and would …
body cells. These bacteria have a central position in human health and disease, and would …