L1CAM in human cancer
P Altevogt, K Doberstein, M Fogel - International journal of …, 2016 - Wiley Online Library
L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described
with important functions in the development of the nervous system. Subsequent work …
with important functions in the development of the nervous system. Subsequent work …
Overview of CD24 as a new molecular marker in ovarian cancer
Ovarian cancer (OC) is the fifth leading cause of cancer‐related death among women. The
high mortality rate is due to lack of early symptoms, late diagnosis, limited treatment options …
high mortality rate is due to lack of early symptoms, late diagnosis, limited treatment options …
TGF-β1 secreted by pancreatic stellate cells promotes stemness and tumourigenicity in pancreatic cancer cells through L1CAM downregulation
Pancreatic stellate cells (PSCs) secrete high levels of transforming growth factor-β1 (TGF-
β1) that contributes to the development of pancreatic ductal adenocarcinoma (PDAC). TGF …
β1) that contributes to the development of pancreatic ductal adenocarcinoma (PDAC). TGF …
Targeting CD24 as a novel immunotherapy for solid cancers
Y Yang, G Zhu, L Yang, Y Yang - Cell Communication and Signaling, 2023 - Springer
Abstract Cluster of differentiation 24 (CD24), a mucin-like highly glycosylated molecule has
been extensively studied as a cancer stem cell marker in a variety of solid cancers. The …
been extensively studied as a cancer stem cell marker in a variety of solid cancers. The …
CD24 blockade as a novel strategy for cancer treatment
Y Wang, H Yu, M Yu, H Liu, B Zhang, Y Wang… - International …, 2023 - Elsevier
The CD24 protein is a heat-stable protein with a small core that undergoes extensive
glycosylation. It is expressed on the surface of various normal cells, including lymphocytes …
glycosylation. It is expressed on the surface of various normal cells, including lymphocytes …
The biological roles of CD24 in ovarian cancer: old story, but new tales
Y Gu, G Zhou, X Tang, F Shen, J Ding… - Frontiers in …, 2023 - frontiersin.org
CD24 is a glycosylphosphatidylinositol linked molecular which expressed in diverse
malignant tumor cells, particular in ovarian carcinoma cells and ovarian carcinoma stem …
malignant tumor cells, particular in ovarian carcinoma cells and ovarian carcinoma stem …
[HTML][HTML] Ovarian cancer stem cells: Can targeted therapy lead to improved progression-free survival?
CLW Haygood, RC Arend, JM Straughn… - World journal of stem …, 2014 - ncbi.nlm.nih.gov
Despite significant effort and research funds, epithelial ovarian cancer remains a very
deadly disease. There are no effective screening methods that discover early stage disease; …
deadly disease. There are no effective screening methods that discover early stage disease; …
CD24, a review of its role in tumor diagnosis, progression and therapy
YH Ni, X Zhao, W Wang - Current gene therapy, 2020 - ingentaconnect.com
CD24, is a mucin-like GPI-anchored molecules. By immunohistochemistry, it is widely
detected in many solid tumors, such as breast cancers, genital system cancers, digestive …
detected in many solid tumors, such as breast cancers, genital system cancers, digestive …
Re-expression of poly/oligo-sialylated adhesion molecules on the surface of tumor cells disrupts their interaction with immune-effector cells and contributes to …
M Jarahian, F Marofi, MS Maashi, M Ghaebi, A Khezri… - Cancers, 2021 - mdpi.com
Simple Summary The immune system consists of various mechanisms contributing to the
battle against cancer cells or hazardous pathogens. However, in cancer progression the …
battle against cancer cells or hazardous pathogens. However, in cancer progression the …
CD24 promotes HCC progression via triggering Notch-related EMT and modulation of tumor microenvironment
X Wan, C Cheng, Q Shao, Z Lin, S Lu, Y Chen - Tumor Biology, 2016 - Springer
CD24 is known as a cell surface molecule in hematopoiesis and also described as a
diagnostic marker for tumors. Previous studies suggested the important role of CD24 in …
diagnostic marker for tumors. Previous studies suggested the important role of CD24 in …