[HTML][HTML] Clinical and biological characterization of skin pigmentation diversity and its consequences on UV impact

S Del Bino, C Duval, F Bernerd - International journal of molecular …, 2018 - mdpi.com
Skin color diversity is the most variable and noticeable phenotypic trait in humans resulting
from constitutive pigmentation variability. This paper will review the characterization of skin …

[HTML][HTML] Overcoming immune evasion in melanoma

K Eddy, S Chen - International journal of molecular sciences, 2020 - mdpi.com
Melanoma is the most aggressive and dangerous form of skin cancer that develops from
transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is …

Melanosomes: biogenesis, properties, and evolution of an ancient organelle

L D'Alba, MD Shawkey - Physiological reviews, 2019 - journals.physiology.org
Melanosomes are organelles that produce and store melanin, a widespread biological
pigment with a unique suite of properties including high refractive index, semiconducting …

The Protective Role of Melanin Against UV Damage in Human Skin

M Brenner, VJ Hearing - Photochemistry and photobiology, 2008 - Wiley Online Library
Human skin is repeatedly exposed to UVR that influences the function and survival of many
cell types and is regarded as the main causative factor in the induction of skin cancer. It has …

Bioinspired melanin‐based optically active materials

M Xiao, MD Shawkey… - Advanced Optical …, 2020 - Wiley Online Library
Melanin is a widespread multifunctional biological pigment that has emerged as a promising
platform for applications in coating, catalysis, energy, drug delivery, and medical therapy …

[HTML][HTML] The regulation of skin pigmentation

Y Yamaguchi, M Brenner, VJ Hearing - Journal of biological chemistry, 2007 - ASBMB
Visible pigmentation of the skin, hair, and eyes depends primarily on the functions of
melanocytes, a very minor population of cells that specialize in the synthesis and distribution …

The red and the black

JD Simon, DN Peles - Accounts of chemical research, 2010 - ACS Publications
“Pigmentation, which is primarily determined by the amount, the type, and the distribution of
melanin, shows a remarkable diversity in human populations, and in this sense, it is an …

New insights into the active site structure and catalytic mechanism of tyrosinase and its related proteins

C Olivares, F Solano - Pigment cell & melanoma research, 2009 - Wiley Online Library
Tyrosinases are widely distributed in nature. They are copper‐containing oxidases
belonging to the type 3 copper protein family, together with catechol oxidases and …

[HTML][HTML] Melanogenesis and the targeted therapy of melanoma

C Li, L Kuai, R Cui, X Miao - Biomolecules, 2022 - mdpi.com
Pigment production is a unique character of melanocytes. Numerous factors are linked with
melanin production, including genetics, ultraviolet radiation (UVR) and inflammation …

Regulation of human skin pigmentation and responses to ultraviolet radiation

Y Miyamura, SG Coelho, R Wolber… - Pigment Cell …, 2007 - Wiley Online Library
Pigmentation of human skin is closely involved in protection against environmental stresses,
in particular exposure to ultraviolet (UV) radiation. It is well known that darker skin is …