Human adenovirus gene expression and replication is regulated through dynamic changes in nucleoprotein structure throughout infection
MR Jennings, RJ Parks - Viruses, 2023 - mdpi.com
Human adenovirus (HAdV) is extremely common and can rapidly spread in confined
populations such as daycare centers, hospitals, and retirement homes. Although HAdV …
populations such as daycare centers, hospitals, and retirement homes. Although HAdV …
Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments
Epstein-Barr virus (EBV) persistently infects people worldwide. Delivery of∼ 170-kb EBV
genomes to nuclei and use of nuclear membrane-less replication compartments (RCs) for …
genomes to nuclei and use of nuclear membrane-less replication compartments (RCs) for …
Novel viral splicing events and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts
Adenovirus is a common human pathogen that relies on host cell processes for transcription
and processing of viral RNA and protein production. Although adenoviral promoters, splice …
and processing of viral RNA and protein production. Although adenoviral promoters, splice …
[HTML][HTML] Proteomic analysis of antiviral innate immunity
JD Albarnaz, MP Weekes - Current Opinion in Virology, 2023 - Elsevier
Highlights•Antiviral innate immunity is regulated by changes in cellular proteins.•These
include changes in abundance, localisation, interaction and PTMs.•Viral immune evasion …
include changes in abundance, localisation, interaction and PTMs.•Viral immune evasion …
Phosphorylation regulates viral biomolecular condensates to promote infectious progeny production
N Grams, M Charman, E Halko, R Lauman… - The EMBO …, 2024 - embopress.org
Biomolecular condensates (BMCs) play important roles in diverse biological processes.
Many viruses form BMCs which have been implicated in various functions critical for the …
Many viruses form BMCs which have been implicated in various functions critical for the …
The protein composition of human adenovirus replication compartments
Human adenoviruses are double-stranded DNA viruses that replicate in the cell nucleus and
induce the formation of replication compartments (RCs) that are critical in viral replication …
induce the formation of replication compartments (RCs) that are critical in viral replication …
Oncolytic virus: A catalyst for the treatment of gastric cancer
J Wang, L Du, X Chen - Frontiers in Oncology, 2022 - frontiersin.org
Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality.
According to the GLOBOCAN 2020 estimates of incidence and mortality for 36 cancers in …
According to the GLOBOCAN 2020 estimates of incidence and mortality for 36 cancers in …
Identifying Protein Interactions with Viral DNA Genomes during Virus Infection
Viruses exploit the host cell machinery to enable infection and propagation. This review
discusses the complex landscape of DNA virus–host interactions, focusing primarily on …
discusses the complex landscape of DNA virus–host interactions, focusing primarily on …
The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles
K Vazaios, Ε Stavrakaki, LB Vogelezang, J Ju… - Molecular Therapy …, 2024 - cell.com
Despite decades of research, the prognosis of high-grade pediatric brain tumors (PBTs)
remains dismal; however, recent cases of favorable clinical responses were documented in …
remains dismal; however, recent cases of favorable clinical responses were documented in …
Omics and systems view of innate immune pathways
D Rathore, MJ Marino, A Nita‐Lazar - Proteomics, 2023 - Wiley Online Library
Multiomics approaches to studying systems biology are very powerful techniques that can
elucidate changes in the genomic, transcriptomic, proteomic, and metabolomic levels within …
elucidate changes in the genomic, transcriptomic, proteomic, and metabolomic levels within …