The quest to slow ageing through drug discovery
L Partridge, M Fuentealba, BK Kennedy - Nature Reviews Drug …, 2020 - nature.com
Although death is inevitable, individuals have long sought to alter the course of the ageing
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials
M Simental-Mendia, A Sanchez-Garcia… - Rheumatology …, 2018 - Springer
Although glucosamine and chondroitin sulfate have showed beneficial effects on joint
tissues in osteoarthritis (OA), their therapeutic use in the clinical setting is still debatable …
tissues in osteoarthritis (OA), their therapeutic use in the clinical setting is still debatable …
Antimicrobial and antiviral activities of durable cotton fabrics treated with nanocomposite based on zinc oxide nanoparticles, acyclovir, nanochitosan, and clove oil
In this study, cotton fabrics based on zinc oxide nanoparticles in situ synthesis, acyclovir,
nanochitosan, and clove oil were treated. The treated cotton fabrics were examined by FTIR …
nanochitosan, and clove oil were treated. The treated cotton fabrics were examined by FTIR …
The Warburg effect and glucose-derived cancer theranostics
RK Tekade, X Sun - Drug Discovery Today, 2017 - Elsevier
Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …
A Broad-Specificity Chitinase from Penicillium oxalicum k10 Exhibits Antifungal Activity and Biodegradation Properties of Chitin
XH Xie, X Fu, XY Yan, WF Peng, LX Kang - Marine Drugs, 2021 - mdpi.com
Penicillium oxalicum k10 isolated from soil revealed the hydrolyzing ability of shrimp chitin
and antifungal activity against Sclerotinia sclerotiorum. The k10 chitinase was produced …
and antifungal activity against Sclerotinia sclerotiorum. The k10 chitinase was produced …
Molecular mechanisms of anticancer effects of Glucosamine
F Zahedipour, R Dalirfardouei, G Karimi… - Biomedicine & …, 2017 - Elsevier
Glucosamine is an amino sugar that is produced naturally in human body. It is an essential
carbohydrate component of many cellular glycoproteins, glycolipids, and …
carbohydrate component of many cellular glycoproteins, glycolipids, and …
Artificial in vitro synthetic enzymatic biosystem for the one-pot sustainable biomanufacturing of glucosamine from starch and inorganic ammonia
D Meng, X Wei, X Bai, W Zhou, C You - Acs Catalysis, 2020 - ACS Publications
Glucosamine is a naturally occurring bioactive amino monosaccharide which is widely used
in the food, cosmetics, and pharmaceutical industries. It is traditionally produced by acid …
in the food, cosmetics, and pharmaceutical industries. It is traditionally produced by acid …
Effect of saccharides coating on antibacterial potential and drug loading and releasing capability of plasma treated polylactic acid films
I Karakurt, K Ozaltin, H Pištěková, D Vesela… - International Journal of …, 2022 - mdpi.com
More than half of the hospital-associated infections worldwide are related to the adhesion of
bacteria cells to biomedical devices and implants. To prevent these infections, it is crucial to …
bacteria cells to biomedical devices and implants. To prevent these infections, it is crucial to …
Computational assessment of the pharmacological profiles of degradation products of chitosan
Chitosan is a natural polymer revealing an increased potential to be used in different
biomedical applications, including drug delivery systems, and tissue engineering. It implies …
biomedical applications, including drug delivery systems, and tissue engineering. It implies …
Dual function of glucosamine in gelatin/hyaluronic acid cryogel to modulate scaffold mechanical properties and to maintain chondrogenic phenotype for cartilage …
Glucosamine (GlcN) fulfills many of the requirements as an ideal component in scaffolds
used in cartilage tissue engineering. The incorporation of GlcN in a gelatin/hyaluronic acid …
used in cartilage tissue engineering. The incorporation of GlcN in a gelatin/hyaluronic acid …