[HTML][HTML] Pathophysiology of obesity and its associated diseases

X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

[HTML][HTML] Adiponectin, obesity, and cancer: clash of the bigwigs in health and disease

S Parida, S Siddharth, D Sharma - International journal of molecular …, 2019 - mdpi.com
Adiponectin is one of the most important adipocytokines secreted by adipocytes and is
called a “guardian angel adipocytokine” owing to its unique biological functions. Adiponectin …

New insight into adiponectin role in obesity and obesity‐related diseases

E Nigro, O Scudiero, ML Monaco… - BioMed research …, 2014 - Wiley Online Library
Obesity is a major health problem strongly increasing the risk for various severe related
complications such as metabolic syndrome, cardiovascular diseases, respiratory disorders …

Curcumin use in pulmonary diseases: State of the art and future perspectives

D Lelli, A Sahebkar, TP Johnston, C Pedone - Pharmacological research, 2017 - Elsevier
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa). It has been used for centuries in Ayurveda (Indian traditional medicine) for the …

[HTML][HTML] Visceral adiposity and systemic inflammation in the obesity paradox in patients with unresectable or metastatic melanoma undergoing immune checkpoint …

JH Lee, S Hyung, J Lee, SH Choi - Journal for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background The obesity paradox is a topic of increasing interest in oncology and
epidemiology research. Although this phenomenon has been observed in melanoma …

[HTML][HTML] Obesity paradox in lung cancer prognosis: evolving biological insights and clinical implications

X Zhang, Y Liu, H Shao, X Zheng - Journal of thoracic oncology, 2017 - Elsevier
The survival rate of lung cancer remains low despite the progress of surgery and
chemotherapy. With the increasing comorbidity of obesity in patients with lung cancer, new …

[HTML][HTML] Curcumin inhibits non-small cell lung cancer cells metastasis through the adiponectin/NF-κb/MMPs signaling pathway

JR Tsai, PL Liu, YH Chen, SH Chou, YJ Cheng… - PloS one, 2015 - journals.plos.org
Adipose tissue is now considered as an endocrine organ involved in metabolic and
inflammatory reactions. Adiponectin, a 244–amino acid peptide hormone, is associated with …

[HTML][HTML] Evolving role of adiponectin in cancer-controversies and update

A Katira, PH Tan - Cancer biology & medicine, 2016 - ncbi.nlm.nih.gov
Adiponectin (APN), an adipokine produced by adipocytes, has been shown to have a critical
role in the pathogenesis of obesity-associated malignancies. Through its receptor …

[HTML][HTML] AdipoRon and other adiponectin receptor agonists as potential candidates in cancer treatments

E Nigro, A Daniele, A Salzillo, A Ragone… - International Journal of …, 2021 - mdpi.com
The high mortality rate together with an ever-growing number of annual cases have defined
neoplastic disorders as “the real 21st-century disease”. Its dubious distinction also results …

[HTML][HTML] Circulating adiponectin levels in various malignancies: an updated meta-analysis of 107 studies

T Wei, P Ye, X Peng, LL Wu, GY Yu - Oncotarget, 2016 - ncbi.nlm.nih.gov
Early detection of cancers is challenging for lack of specific biomarkers. Adiponectin is an
adipokine predominantly derived from adipocytes and hypoadiponectinemia has been …