Nitric oxide (NO) can modulate arterial stiffness by regulating both functional and structural
changes in the arterial wall. Tissue transglutaminase (TG2) has been shown to contribute to …

We present a protocol for measuring in vivo aortic stiffness in mice using high-resolution
ultrasound imaging. Aortic diameter is measured by ultrasound and aortic blood pressure is …

Sympathetic nerve activity (SNA) regulates blood pressure by controlling vascular smooth
muscle tone in peripheral arterioles. However, the function of SNA on vascular smooth …

Despite significant advances in scientific research and clinical medicine, cardiovascular
disease remains the major cause of death worldwide (1). It claimed the lives of almost …

This dissertation illustrates the role of nitric oxide (NO) in regulating coronary tone and how
impairment of NO bioavailability not only influences coronary vasoregulation but also the …