[HTML][HTML] Trends in drug-and vaccine-based dissolvable microneedle materials and methods of fabrication

LE Moore, S Vucen, AC Moore - European Journal of Pharmaceutics and …, 2022 - Elsevier
Microneedle patches, also called microarray patches (MAP), are an emerging technology for
delivery and sampling of drugs, vaccines and other materials. This review focuses on the …

Research progress of microneedles in the treatment of melanoma

X Li, Z Zhao, M Zhang, G Ling, P Zhang - Journal of controlled release, 2022 - Elsevier
Melanoma is an aggressive malignancy deriving from melanocytes, which is characterized
by high tendency of metastases and mortality rate. Current therapies for melanoma, like …

Transdermal delivery of Cu-doped polydopamine using microneedles for photothermal and chemodynamic synergistic therapy against skin melanoma

G Song, Y Sun, T Liu, X Zhang, Z Zeng, R Wang… - Chemical Engineering …, 2021 - Elsevier
Multimodal nanoformulations with limited side-effects for tumor theranostics that catalyze a
cascade of intracellular reactions show great potentials for tumor treatment with high …

Advances in natural polymer‐based transdermal drug delivery systems for tumor therapy

W Han, F Liu, Y Li, G Liu, H Li, Y Xu, S Sun - Small, 2023 - Wiley Online Library
As an alternative to traditional oral and intravenous injections with limited efficacy,
transdermal drug delivery (TDD) has shown great promise in tumor treatment. Over the past …

Multifunctional covalent organic framework-based microneedle patch for melanoma treatment

P Li, CH Liu, YY Zhao, DD Cao, BZ Chen… - …, 2023 - ACS Publications
Melanoma is resistant to conventional chemotherapy and radiotherapy. Therefore, it is
essential to develop a targeted, low-toxic, and minimally invasive treatment. Here, DTIC/ICG …

Antioxidant enzymes sequestered within lipid–polymer hybrid nanoparticles for the local treatment of inflammatory bowel disease

Z Le, Z He, H Liu, L Liu, Z Liu… - ACS Applied Materials & …, 2021 - ACS Publications
The local treatment of inflammatory bowel disease (IBD) by enzyme therapeutics is
challenging owing to hostile environments in the gastrointestinal tract, leading to the …

Co-encapsulation of drugs for topical application—A review

JA Ataide, JC Coco, ÉM Dos Santos, V Beraldo-Araujo… - Molecules, 2023 - mdpi.com
Achieving the best possible outcome for the therapy is the main goal of a medicine.
Therefore, nanocarriers and co-delivery strategies were invented to meet this need, as they …

Photoresponsive polymeric microneedles: An innovative way to monitor and treat diseases

P Singh, B Youden, A Carrier, K Oakes… - Journal of Controlled …, 2023 - Elsevier
Microneedles (MN) technology is an emerging technology for the transdermal delivery of
therapeutics. When combined with photoresponsive (PR) materials, MNs can deliver …

[Retracted] Development of Microneedle Patch Loaded with Bacopa monnieri Solid Lipid Nanoparticles for the Effective Management of Parkinson's Disease

D Joy, J Jose, S Bibi, A Bandiwadekar… - Bioinorganic …, 2022 - Wiley Online Library
The demand for drug delivery systems (DDS) to treat Parkinson's disease (PD) is still high,
and microneedle (MN) assisted transdermal DDS offers enormous potential. Herbal …

Inter-Organelle Contact Sites Mediate the Intracellular Antioxidant Activity of Platinum Nanozymes: A New Perspective on Cell–Nanoparticle Interaction and Signaling

V Migliaccio, N Blal, M De Girolamo… - … Applied Materials & …, 2023 - ACS Publications
The catalytic and antioxidant properties of platinum nanoparticles (PtNPs) make them
promising candidates for several applications in nanomedicine. However, an open issue …