Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Effectiveness, core elements, and moderators of response of cognitive remediation for schizophrenia: a systematic review and meta-analysis of randomized clinical …

A Vita, S Barlati, A Ceraso, G Nibbio, C Ariu… - JAMA …, 2021 - jamanetwork.com
Importance Cognitive impairment is a core feature of schizophrenia, with negative
consequences on functional outcomes. Although cognitive remediation (CR) is effective and …

The clinical characterization of the patient with primary psychosis aimed at personalization of management

M Maj, J van Os, M De Hert, W Gaebel… - World …, 2021 - Wiley Online Library
The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …

Nonsocial and social cognition in schizophrenia: current evidence and future directions

MF Green, WP Horan, J Lee - World psychiatry, 2019 - Wiley Online Library
Cognitive impairment in schizophrenia involves a broad array of nonsocial and social
cognitive domains. It is a core feature of the illness, and one with substantial implications for …

Social cognition in schizophrenia

MF Green, WP Horan, J Lee - Nature Reviews Neuroscience, 2015 - nature.com
Individuals with schizophrenia exhibit impaired social cognition, which manifests as
difficulties in identifying emotions, feeing connected to others, inferring people's thoughts …

[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

Aerobic exercise improves cognitive functioning in people with schizophrenia: a systematic review and meta-analysis

J Firth, B Stubbs, S Rosenbaum… - Schizophrenia …, 2017 - academic.oup.com
Cognitive deficits are pervasive among people with schizophrenia and treatment options are
limited. There has been an increased interest in the neurocognitive benefits of exercise, but …

Two distinct neuroanatomical subtypes of schizophrenia revealed using machine learning

GB Chand, DB Dwyer, G Erus, A Sotiras, E Varol… - Brain, 2020 - academic.oup.com
Neurobiological heterogeneity in schizophrenia is poorly understood and confounds current
analyses. We investigated neuroanatomical subtypes in a multi-institutional multi-ethnic …

The development of social cognition in adolescence: An integrated perspective

EJ Kilford, E Garrett, SJ Blakemore - Neuroscience & Biobehavioral …, 2016 - Elsevier
Social cognitive processes are critical in navigating complex social interactions and are
associated with a network of brain areas termed the 'social brain'. Here, we describe the …

[HTML][HTML] Social cognitive dysfunction as a clinical marker: A systematic review of meta-analyses across 30 clinical conditions

J Cotter, K Granger, R Backx, M Hobbs, CY Looi… - Neuroscience & …, 2018 - Elsevier
Social cognition includes a range of cognitive processes that help individuals to understand
how others think and feel. There is emerging evidence that social cognitive deficits may …