Synthetic biology routes to bio-artificial intelligence

DN Nesbeth, A Zaikin, Y Saka, MC Romano… - Essays in …, 2016 - portlandpress.com
The design of synthetic gene networks (SGNs) has advanced to the extent that novel genetic
circuits are now being tested for their ability to recapitulate archetypal learning behaviours …

Chimera states in hybrid coupled neuron populations

A Calim, JJ Torres, M Ozer, M Uzuntarla - Neural Networks, 2020 - Elsevier
Here we study the emergence of chimera states, a recently reported phenomenon referring
to the coexistence of synchronized and unsynchronized dynamical units, in a population of …

Learning by selective plasmid loss for intracellular synthetic classifiers

O Kanakov, S Chen, A Zaikin - Chaos, Solitons & Fractals, 2024 - Elsevier
We propose a learning mechanism for intracellular synthetic genetic classifiers based on the
selective elimination (curing) of plasmids bearing parts of the classifier circuit. Our focus is …

Controllability of fractional-order directed complex networks

H Zhang, DY Chen, BB Xu, RF Zhang - Modern Physics Letters B, 2014 - World Scientific
This paper is a step forward to generalize the fundamentals of the conventional
controllability in fractional-order complex networks. First, we discuss the existence of …

Mammalian brain as a network of networks

V Samborska, S Gordleeva, E Ullner… - Opera Medica et …, 2016 - cyberleninka.ru
A conspicuous ability of the mammalian brain to integrate and process huge amount of
spatial, visual and temporal stimuli is a result of its enormous structural complexity …

Modelling timing in blood cancers

L Talarmain - 2021 - repository.cam.ac.uk
Dysregulation of biological processes in normal cells can lead to the abnormal growth of
tumours. Oncogenesis requires the acquisition of advantageous mutations to expand in a …

Multiple regulation mechanisms of bacterial quorum sensing

P Kumberger, C Kuttler, P Czuppon, BA Hense - Biomath, 2016 - biomath.math.bas.bg
Many bacteria have developed a possibility to recognise aspects of their environment or to
communicate with each other by chemical signals. The so-called Quorum sensing (QS) is a …

Bacterial Cells as Engineered Chassis

Y Borg, A Templar, D Schofield… - Synthetic Biology …, 2016 - api.taylorfrancis.com
Since the 1970s E. coli has been the standard biological vehicle for propagation of
recombinant DNA, transgenic production of proteins and, via expression of recombinant …

Chimera states in hybrid coupled neuron populations

J Torres Agudo, A Calim, M Ozer, M Uzuntarla - 2020 - digibug.ugr.es
Here we study the emergence of chimera states, a recently reported phenomenon referring
to the coexistence of synchronized and unsynchronized dynamical units, in a population of …

Complex and Surprising Dynamics in Gene Regulatory Networks

S Chen, A Zaikin, S Chen, A Zaikin - Quantitative Physiology: Systems …, 2020 - Springer
Interacting genetic networks are governed by mechanisms describing nonlinear dynamics of
such elements. As a result, several surprising effects can appear. Here we show how …