Analytical techniques for metabolomic studies: A review

K Segers, S Declerck, D Mangelings, YV Heyden… - Bioanalysis, 2019 - Taylor & Francis
Metabolomics is the comprehensive study of small-molecule metabolites. Obtaining a wide
coverage of the metabolome is challenging because of the broad range of physicochemical …

Understanding glycaemic control and current approaches for screening antidiabetic natural products from evidence-based medicinal plants

C Lankatillake, T Huynh, DA Dias - Plant Methods, 2019 - Springer
Abstract Type 2 Diabetes Mellitus has reached epidemic proportions as a result of over-
nutrition and increasingly sedentary lifestyles. Current therapies, although effective, are not …

Metabolomics analysis of alloxan-induced diabetes in mice using UPLC–Q-TOF-MS after Crassostrea gigas polysaccharide treatment

G Zhao, X Hou, X Li, M Qu, C Tong, W Li - International journal of biological …, 2018 - Elsevier
Diabetes has become a global and serious health issues which causes a variety of
complications. This study aims to explore the hypoglycemic effect of Crassostrea gigas …

1H NMR-Based Metabolomics Coupled With Molecular Docking Reveal the Anti-Diabetic Effects and Potential Active Components of Berberis vernae on Type 2 …

Q Li, C Zhao, Y Zhang, H Du, T Xu, X Xu… - Frontiers in …, 2020 - frontiersin.org
The dried stem bark of Berberis vernae CK Schneid., known as “Xiao-bo-pi” in Chinese, is a
representative anti-diabetic herb in traditional Tibetan medical system. However, its anti …

Metabolic profiling analysis of the effect and mechanism of gushiling capsule in rabbits with glucocorticoid-induced osteonecrosis of the femoral head

R Mei, D Chen, D Zhong, G Li, S Lin, G Zhang… - Frontiers in …, 2022 - frontiersin.org
Gushiling capsule (GSLC) is an effective traditional Chinese medicine for the treatment of
glucocorticoid-induced osteonecrosis of the femoral head (GIONFH). This study established …

[HTML][HTML] A metabolomic study on early detection of steroid-induced avascular necrosis of the femoral head

X Ren, W Fan, Z Shao, K Chen, X Yu, Q Liang - Oncotarget, 2018 - ncbi.nlm.nih.gov
The early and accurate diagnosis of steroid-induced avascular necrosis of the femoral head
(SANFH) is appealing considering its irreversible progression and serious consequence for …

Characterizing serum metabolic alterations of Alzheimer's disease and intervention of Shengmai-San by ultra-performance liquid chromatography/electrospray …

S Lu, Y Han, H Chu, L Kong, A Zhang, G Yan, H Sun… - Food & function, 2017 - pubs.rsc.org
Alzheimer's disease (AD) is a chronic and multi-factor-induced neurodegenerative disorder.
The development of a single-target treatment strategy for AD has not been successful …

Integrated metallomic and metabolomic profiling of plasma and tissues provides deep insights into the protective effect of raw and salt-processed Achyranthes …

Y Tao, S Huang, J Yan, W Li, B Cai - Journal of ethnopharmacology, 2019 - Elsevier
Abstract Ethnopharmacological relevance Achyranthes bidentata Blume (AB) is a well-
known traditional Chinese medicine for treating osteoporosis and bone fracture. In the …

Mechanism of YLTZ on glycolipid metabolism based on UPLC/TOF/MS metabolomics

J Zhuo, D Cai, K Xie, H Gan, S Li, X Huang… - … of Chromatography B, 2018 - Elsevier
Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by dysfunction of
glycolipid metabolism. YLTZ is used to treat hyperlipidemia, yet its hypolipidemic and …

[HTML][HTML] 基于脂质组学技术的中药降脂作用研究

王美琴, 胡冰莹, 王润婧, 燕攀, 杜支凤, 姜宏梁 - 药学学报, 2021 - html.rhhz.net
高脂血症是一种常见的血脂异常疾病, 是导致各种心血管疾病的重要危险因素.
中药具有疗效确切, 不良反应少, 作用温和等优点, 广泛应用于预防和治疗高脂血症. 然而 …