Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

Hypoxic-ischemic and traumatic brain injuries are leading causes of long-term mortality and
disability in infants and children. Although several preclinical models using rodents of …

Traumatic brain injury (TBI) is a significant clinical problem with few therapeutic interventions
successfully translated to the clinic. Increased importance on the progressive, long-term …

Neural stem cells persist in the adult mammalian forebrain and are a potential source of
neurons for repair after brain injury. The two main areas of persistent neurogenesis, the …

Traumatic brain injury (TBI) has become the signature wound of wars in Afghanistan and
Iraq. Injury may result from a mechanical force, a rapid acceleration-deceleration movement …

Adult neurogenesis is a widespread trait of vertebrates; however, the degree of this ability
and the underlying activity of the adult neural stem cells differ vastly among species. In …

Traumatic brain injury and stroke are major causes of mortality and morbidity worldwide.
Unfortunately, almost all phase-III neuroprotective clinical trials for stroke and traumatic brain …

Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities
impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result …

Current experimental models of blast injuries used to study blast-induced neurotrauma
(BINT) vary widely, which makes the comparison of the experimental results extremely …

In the developing brain, cell migration is a crucial process for structural organization, and is
therefore highly regulated to allow the correct formation of complex networks, wiring …