The entomology literature has historically suggested insects cannot feel pain, leading to
their exclusion from ethical debates and animal welfare legislation. However, there may be …

Among the many wonders of nature, the sense of smell of the fly Drosophila melanogaster
might seem, at first glance, of esoteric interest. Nevertheless, for over a century, the 'nose'of …

The neural circuits responsible for animal behavior remain largely unknown. We summarize
new methods and present the circuitry of a large fraction of the brain of the fruit fly …

Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …

Nervous systems contain sensory neurons, local neurons, projection neurons, and motor
neurons. To understand how these building blocks form whole circuits, we must distil these …

The hemibrain connectome provides large-scale connectivity and morphology information
for the majority of the central brain of Drosophila melanogaster. Using this data set, we …

Principles of Neurobiology, Second Edition presents the major concepts of neuroscience
with an emphasis on how we know what we know. The text is organized around a series of …

Animals exhibit innate behaviours to a variety of sensory stimuli including olfactory cues. In
Drosophila, one higher olfactory centre, the lateral horn (LH), is implicated in innate …

High-resolution electron microscopy of nervous systems has enabled the reconstruction of
synaptic connectomes. However, we do not know the synaptic sign for each connection (ie …

Animals exhibit innate and learned preferences for temperature and humidity—conditions
critical for their survival and reproduction. Leveraging a whole-brain electron microscopy …