Applications of phyto-nanotechnology for the treatment of neurodegenerative disorders

T Bhattacharya, GAB Soares, H Chopra, MM Rahman… - Materials, 2022 - mdpi.com
The strategies involved in the development of therapeutics for neurodegenerative disorders
are very complex and challenging due to the existence of the blood-brain barrier (BBB), a …

Cell-derived nanovesicle-mediated drug delivery to the brain: principles and strategies for vesicle engineering

Y Liang, Z Iqbal, J Lu, J Wang, H Zhang, X Chen… - Molecular Therapy, 2023 - cell.com
Developing strategies toward safe and effective drug delivery into the central nervous
system (CNS) with improved targeting abilities and reduced off-target effects is crucial. CNS …

[HTML][HTML] Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance

MM Rahman, MR Islam, S Akash… - Biomedicine & …, 2022 - Elsevier
Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments,
such as varieties of malignancies, neurological problems, and infectious illnesses …

Unlocking the power of exosomes for crossing biological barriers in drug delivery

RO Elliott, M He - Pharmaceutics, 2021 - mdpi.com
Since the 2013 Nobel Prize was awarded for the discovery of vesicle trafficking, a subgroup
of nanovesicles called exosomes has been driving the research field to a new regime for …

The multifaceted role of curcumin in advanced nanocurcumin form in the treatment and management of chronic disorders

P Tagde, P Tagde, F Islam, S Tagde, M Shah… - Molecules, 2021 - mdpi.com
Curcumin is the primary polyphenol in turmeric's curcuminoid class. It has a wide range of
therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic …

Nanomaterials for photothermal and photodynamic cancer therapy

B Nasseri, E Alizadeh, F Bani, S Davaran… - Applied Physics …, 2022 - pubs.aip.org
In recent years, the role of optically sensitive nanomaterials has become powerful moieties
in therapeutic techniques and has become particularly emphasized. Currently, by the …

Brain delivery of quercetin-loaded exosomes improved cognitive function in AD mice by inhibiting phosphorylated tau-mediated neurofibrillary tangles

Y Qi, L Guo, Y Jiang, Y Shi, H Sui, L Zhao - Drug Delivery, 2020 - Taylor & Francis
It is reported that quercetin (Que) can prevent tau pathology and induce neuroprotection by
improving cognitive and functional symptoms in the treatment of Alzheimer's disease (AD) …

Transcytosis-enabled active extravasation of tumor nanomedicine

Q Zhou, J Li, J Xiang, S Shao, Z Zhou, J Tang… - Advanced Drug Delivery …, 2022 - Elsevier
Extravasation is the first step for nanomedicines in circulation to reach targeted solid tumors.
Traditional nanomedicines have been designed to extravasate into tumor interstitium …

Nanomedicine-based technologies and novel biomarkers for the diagnosis and treatment of Alzheimer's disease: from current to future challenges

A Cano, P Turowski, M Ettcheto, JT Duskey… - Journal of …, 2021 - Springer
Increasing life expectancy has led to an aging population, which has consequently
increased the prevalence of dementia. Alzheimer's disease (AD), the most common form of …

Applications of the ROS-responsive thioketal linker for the production of smart nanomedicines

A Rinaldi, R Caraffi, MV Grazioli, N Oddone, L Giardino… - Polymers, 2022 - mdpi.com
Reactive oxygen species (ROS)-sensitive drug delivery systems (DDS) specifically
responding to altered levels of ROS in the pathological microenvironment have emerged as …