Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility

TK Karikari, NJ Ashton, G Brinkmalm… - Nature Reviews …, 2022 - nature.com
Well-authenticated biomarkers can provide critical insights into the biological basis of
Alzheimer disease (AD) to enable timely and accurate diagnosis, estimate future burden and …

Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration

F Gonzalez-Ortiz, M Turton, PR Kac, D Smirnov… - Brain, 2023 - academic.oup.com
Blood-based biomarkers for amyloid beta and phosphorylated tau show good diagnostic
accuracies and agreements with their corresponding CSF and neuroimaging biomarkers in …

Time course and diagnostic utility of NfL, tau, GFAP, and UCH-L1 in subacute and chronic TBI

P Shahim, A Politis, A Van Der Merwe, B Moore… - Neurology, 2020 - AAN Enterprises
Objective To determine whether neurofilament light (NfL), glial fibrillary acidic protein
(GFAP), tau, and ubiquitin C-terminal hydrolase-L1 (UCH-L1) measured in serum relate to …

An update on diagnostic and prognostic biomarkers for traumatic brain injury

KK Wang, Z Yang, T Zhu, Y Shi… - Expert review of …, 2018 - Taylor & Francis
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …

[HTML][HTML] Biomarkers in sports and exercise: tracking health, performance, and recovery in athletes

EC Lee, MS Fragala, SA Kavouras… - The Journal of …, 2017 - journals.lww.com
Abstract Lee, EC, Fragala, MS, Kavouras, SA, Queen, RM, Pryor, JL, and Casa, DJ.
Biomarkers in sports and exercise: tracking health, performance, and recovery in athletes. J …

Traumatic brain injuries

K Blennow, DL Brody, PM Kochanek, H Levin… - Nature reviews Disease …, 2016 - nature.com
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …

Traumatic brain injury and Alzheimer's disease: the cerebrovascular link

J Ramos-Cejudo, T Wisniewski, C Marmar… - …, 2018 - thelancet.com
Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological
disorders, whose complex relationship is not completely understood. Cerebrovascular …

The neuropathology of traumatic brain injury

AC Mckee, DH Daneshvar - Handbook of clinical neurology, 2015 - Elsevier
Traumatic brain injury, a leading cause of mortality and morbidity, is divided into three
grades of severity: mild, moderate, and severe, based on the Glasgow Coma Scale, the loss …

Diagnosis, prognosis, and clinical management of mild traumatic brain injury

HS Levin, RR Diaz-Arrastia - The Lancet Neurology, 2015 - thelancet.com
Concussion and mild traumatic brain injury (TBI) are interchangeable terms to describe a
common disorder with substantial effects on public health. Advances in brain imaging, non …