[HTML][HTML] Regulation of antiviral innate immune signaling and viral evasion following viral genome sensing

K Chathuranga, A Weerawardhana… - … & Molecular Medicine, 2021 - nature.com
A harmonized balance between positive and negative regulation of pattern recognition
receptor (PRR)-initiated immune responses is required to achieve the most favorable …

Resolvins and cysteinyl-containing pro-resolving mediators activate resolution of infectious inflammation and tissue regeneration

CN Serhan, N Chiang - Prostaglandins & other lipid mediators, 2023 - Elsevier
This review is a synopsis of the main points from the opening presentation by the authors in
the Resolution of Inflammation session at the 8th European Workshop on Lipid Mediators …

[HTML][HTML] Altered m6A modification of specific cellular transcripts affects flaviviridae infection

NS Gokhale, ABR McIntyre, MD Mattocks, CL Holley… - Molecular cell, 2020 - cell.com
The RNA modification N 6-methyladenosine (m 6 A) modulates mRNA fate and thus affects
many biological processes. We analyzed m 6 A across the transcriptome following infection …

Golgi apparatus: an emerging platform for innate immunity

Y Tao, Y Yang, R Zhou, T Gong - Trends in cell biology, 2020 - cell.com
The Golgi apparatus serves as a receiving station where proteins from the endoplasmic
reticulum (ER) are further processed before being sent to other cellular compartments. In …

Signaling from the RNA sensor RIG-I is regulated by ufmylation

DL Snider, M Park, KA Murphy… - Proceedings of the …, 2022 - National Acad Sciences
The RNA-binding protein RIG-I is a key initiator of the antiviral innate immune response. The
signaling that mediates the antiviral response downstream of RIG-I is transduced through …

Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity

R Safi, M Sánchez‐Álvarez, M Bosch… - Immunological …, 2023 - Wiley Online Library
Microbes have developed many strategies to subvert host organisms, which, in turn, evolved
several innate immune responses. As major lipid storage organelles of eukaryotes, lipid …

Cysteinyl-specialized proresolving mediators link resolution of infectious inflammation and tissue regeneration via TRAF3 activation

N Chiang, X de la Rosa, S Libreros… - Proceedings of the …, 2021 - National Acad Sciences
The recently elucidated proresolving conjugates in tissue regeneration (CTR) maresin-CTR
(MCTR), protectin-CTR (PCTR), and resolvin-CTR (RCTR), termed cysteinyl-specialized …

The mRNA Cap 2′-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes

GD Williams, NS Gokhale, DL Snider, SM Horner - Msphere, 2020 - Am Soc Microbiol
Type I interferons (IFN) initiate an antiviral state through a signal transduction cascade that
leads to the induction of hundreds of IFN-stimulated genes (ISGs) to restrict viral infection …

A review of shrimp cellular receptors for WSSV: Potential targets for antiviral strategies in shrimp aquaculture

T Encinas-Garcia, F Mendoza-Cano… - Reviews in Fisheries …, 2024 - Taylor & Francis
The white spot syndrome virus (WSSV) is a highly lethal pathogen for several crustacean
species, which implies that this virus has caused high mortalities and significant economic …

Dual function of Rab1A in secretion and autophagy: hypervariable domain dependence

V Gyurkovska, R Murtazina, SF Zhao… - Life Science …, 2023 - life-science-alliance.org
We currently understand how the different intracellular pathways, secretion, endocytosis,
and autophagy are regulated by small GTPases. In contrast, it is unclear how these …