Constituents from Salvia Species and Their Biological Activities

YB Wu, ZY Ni, QW Shi, M Dong, H Kiyota… - Chemical …, 2012 - ACS Publications
The Lamiaceae (formerly Labiatae), a widespread family, comprises 220 genera and 4000
species distributed throughout most of the world as annuals and perennial plants. The …

Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza

Z Jiang, W Gao, L Huang - Frontiers in Pharmacology, 2019 - frontiersin.org
Salvia miltiorrhiza Bunge, a member of the Lamiaceae family, is valued in traditional
Chinese Medicine. Its dried root (named Danshen) has been used for hundreds of years …

Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice

SH Kwon, HK Lee, JA Kim, SI Hong, HC Kim… - European journal of …, 2010 - Elsevier
Chlorogenic acid is a major polyphenolic component of many plants and beverages, and is
particularly abundant in coffee. We evaluated the neuroprotective effects of chlorogenic acid …

Acetylcholinesterase inhibitors from plants and fungi

PJ Houghton, Y Ren, MJ Howes - Natural product reports, 2006 - pubs.rsc.org
Covering: January 1980 to August 2005This review describes 183 compounds obtained
from plants and fungi which have been shown to inhibit acetylcholinesterase. The …

Natural products as a source of Alzheimer's drug leads

P Williams, A Sorribas, MJR Howes - Natural product reports, 2011 - pubs.rsc.org
Covering: up to 2010 This review focuses on recent developments in the use of natural
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …

New developments in the chemistry and biology of the bioactive constituents of Tanshen

X Wang, SL Morris‐Natschke… - Medicinal research …, 2007 - Wiley Online Library
Tanshen, the rhizome of Salvia miltiorrhiza Bunge, has been used in Chinese traditional
medicine (TCM) for multiple therapeutic remedies. The major constituents of Tanshen …

Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility

J Cheung, EN Gary, K Shiomi… - ACS medicinal …, 2013 - ACS Publications
Acetylcholinesterase is a critical enzyme that regulates neurotransmission by degrading the
neurotransmitter acetylcholine in synapses of the nervous system. It is an important target for …

Uses and abuses of in vitro tests in ethnopharmacology: visualizing an elephant

PJ Houghton, MJ Howes, CC Lee… - Journal of …, 2007 - Elsevier
Although in vivo models give a more accurate reflection of the activity of substances used in
traditional medicine, their use in many countries is severely restricted due to economic and …

[图书][B] Thin layer chromatography in phytochemistry

M Waksmundzka-Hajnos, J Sherma, T Kowalska - 2008 - taylorfrancis.com
Thin layer chromatography (TLC) is increasingly used in the fields of plant chemistry,
biochemistry, and molecular biology. Advantages such as speed, versatility, and low cost …

Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion

JY Han, JY Fan, Y Horie, S Miura, DH Cui… - Pharmacology & …, 2008 - Elsevier
Ischemia and reperfusion (I/R) exerts multiple insults in microcirculation, frequently
accompanied by endothelial cell injury, enhanced adhesion of leukocytes, macromolecular …