Medicinal importance, coordination chemistry with selected metals (Cu, Ag, Au) and chemosensing of thiourea derivatives. A review
Thiourea and its derivatives are versatile compounds used in several fields of life ranging
from medicinal to chemosensor applications. In this review article, generally used …
from medicinal to chemosensor applications. In this review article, generally used …
Discovery of new anticancer thiourea-azetidine hybrids: Design, synthesis, in vitro antiproliferative, SAR, in silico molecular docking against VEGFR-2, ADMET, toxicity …
DR Parmar, JY Soni, R Guduru, RH Rayani… - Bioorganic …, 2021 - Elsevier
With the aim to discover potent and novel antitumor agents, a series of thiourea compounds
bearing 3-(4-methoxyphenyl) azetidine moiety were designed according to the essential …
bearing 3-(4-methoxyphenyl) azetidine moiety were designed according to the essential …
Nimesulide analogues: From anti-inflammatory to antitumor agents
M Catarro, JL Serrano, SS Ramos, S Silvestre… - Bioorganic …, 2019 - Elsevier
Nimesulide is a nonsteroidal anti-inflammatory drug possessing analgesic and antipyretic
properties. This drug is considered a selective cyclooxygenase-2 (COX-2) inhibitor and …
properties. This drug is considered a selective cyclooxygenase-2 (COX-2) inhibitor and …
[PDF][PDF] armacia Farmacia F
A ANDRIEŞ - 2014 - researchgate.net
Squalene is a natural dehydrotriterpenic hydrocarbon (C30H50) with six double bonds, an
intermediate for the biosynthesis of phytosterol/cholesterol in plants/animals and humans …
intermediate for the biosynthesis of phytosterol/cholesterol in plants/animals and humans …
Experimental and computational analysis of 1-(4-chloro-3-nitrophenyl)-3-(3, 4-dichlorophenyl) thiourea
A Bielenica, S Beegum, YS Mary, YS Mary… - Journal of Molecular …, 2020 - Elsevier
This manuscript presents the computational and experimental studies of a new thiourea
derivative 1-(4-chloro-3-nitrophenyl)-3-(3, 4-dichlorophenyl) thiourea (CNDCT). Scaled …
derivative 1-(4-chloro-3-nitrophenyl)-3-(3, 4-dichlorophenyl) thiourea (CNDCT). Scaled …
Investigation of the reactivity properties of a thiourea derivative with anticancer activity by DFT and MD simulations
YS Mary, YS Mary, A Bielenica, S Armaković… - Journal of Molecular …, 2021 - Springer
Abstract Spectroscopic analysis of 1-(2-fluorophenyl)-3-[3-(trifluoromethyl) phenyl] thiourea
(FPTT) is reported. Experimental and theoretical analyses of FPTT, with molecular dynamics …
(FPTT) is reported. Experimental and theoretical analyses of FPTT, with molecular dynamics …
Design and synthesis of thiourea derivatives containing a benzo [5, 6] cyclohepta [1, 2-b] pyridine moiety as potential antitumor and anti-inflammatory agents
W Liu, J Zhou, T Zhang, H Zhu, H Qian, H Zhang… - Bioorganic & medicinal …, 2012 - Elsevier
Thiourea derivatives (6a–e) were developed and screened for antitumor and anti-
inflammatory activity. Most of the compounds exhibited growth inhibitory effects comparable …
inflammatory activity. Most of the compounds exhibited growth inhibitory effects comparable …
Disubstituted thiourea derivatives and their activity on CNS: Synthesis and biological evaluation
A series of new thiourea derivatives of 1, 2, 4-triazole have been synthesized. The difference
in structures of obtained compounds are directly connected with the kind of isothiocyanate …
in structures of obtained compounds are directly connected with the kind of isothiocyanate …
Design, molecular docking, and molecular dynamics of thiourea-iron (III) metal complexes as NUDT5 inhibitors for breast cancer treatment
In research, anticancer agents, such as thiourea derivative compounds, and metal
complexes, such as those complexed with iron (III) metal, are often studied. The metal …
complexes, such as those complexed with iron (III) metal, are often studied. The metal …
Synthesis and biological evaluation of novel indole-derived thioureas
G Sanna, S Madeddu, G Giliberti, S Piras, M Struga… - Molecules, 2018 - mdpi.com
A series of 2-(1 H-indol-3-yl) ethylthiourea derivatives were prepared by condensation of 2-
(1 H-indol-3-yl) ethanamine with appropriate aryl/alkylisothiocyanates in anhydrous media …
(1 H-indol-3-yl) ethanamine with appropriate aryl/alkylisothiocyanates in anhydrous media …