Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

The catalysis by primary and secondary amines of electrophilic substitution reactions in the
R-position of carbonyl compounds and related reactions via enamine intermediates is called …

Abstract The legacy of Gilbert Newton Lewis (1875–1946) pervades the lexicon of chemical
bonding and reactivity. The power of his concept of donor–acceptor bonding is evident in the …

Organocatalysis has captured the imagination of a significant group of synthetic chemists.
Much of the mechanistic understanding of these reactions has come from computational …

Catalysis with chiral secondary amines (asymmetric aminocatalysis) has become a well‐
established and powerful synthetic tool for the chemo‐and enantioselective functionalization …

After an initial period of validating asymmetric organocatalysis by using a wide range of
important model reactions that constitute the essential tools of organic synthesis, the time …

The field of asymmetric organocatalysis is rapidly developing and attracts an increasing
number of research groups around the world. Here we present a brief overview of this area …

The development of a general organocatalyst for the α-functionalization of aldehydes, via an
enamine intermediate, is presented. Based on optically active α, α-diarylprolinol silyl ethers …

Mechanisms in aminocatalysis - Chemical Communications (RSC Publishing) DOI:10.1039/C0CC02417A
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/C0CC02417A …

During the last six years the asymmetric catalysis of carbonyl transformations via iminium ion
and enamine intermediates using chiral amines as organocatalysts has grown most …