Technological advances in cryo-EM in recent years have given rise to detailed atomic
structures of bacteriophage tail tubes—a class of filamentous protein assemblies that could …

Clostridium difficile, now reclassified as Clostridioides difficile, is the causative agent of C.
difficile infections (CDI). CDI is particularly challenging in healthcare settings because highly …

Alphaproteobacteria, which are the most abundant microorganisms of temperate oceans,
produce phage-like particles called gene transfer agents (GTAs) that mediate lateral gene …

CrAssphage and related viruses of the order Crassvirales (hereafter referred to as
crassviruses) were originally discovered by cross-assembly of metagenomic sequences …

The T5 family of viruses are tailed bacteriophages characterized by a long non-contractile
tail. The bacteriophage DT57C is closely related to the paradigmal T5 phage, though it …

Herpesviruses include many important human pathogens such as herpes simplex virus,
cytomegalovirus, varicella-zoster virus, and the oncogenic Epstein–Barr virus and Kaposi …

The vast majority of phages, bacterial viruses, possess a tail ensuring host recognition, cell
wall perforation and safe viral DNA transfer from the capsid to the host cytoplasm. Long …

Double-stranded DNA bacteriophages package their genome at high pressure inside a
procapsid through the portal, an oligomeric ring protein located at a unique capsid vertex …

Highlights•Siphophage tails share a common core architecture despite great sequence
diversity.•Myophage tails and phage-related injection systems also share the same …

Numerous viruses package their dsDNA genome into preformed capsids through a portal
gatekeeper that is subsequently closed. We report the structure of the DNA gatekeeper …