A network-biology perspective of microRNA function and dysfunction in cancer
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …
and consequently have roles in many pathologies, including cancer. These small non …
Triple negative breast cancer in the era of miRNA
The objective of this review is to elucidate the role of miRNAs in triple negative breast cancer
(TNBC). To achieve our goal, we searched databases such as PubMed, ScienceDirect …
(TNBC). To achieve our goal, we searched databases such as PubMed, ScienceDirect …
LightGBM: an effective miRNA classification method in breast cancer patients
D Wang, Y Zhang, Y Zhao - … of the 2017 international conference on …, 2017 - dl.acm.org
miRNAs are small noncoding RNA molecules, mainly responsible for post-transcriptional
control of gene expressions. Machine learning is becoming more and more widely used in …
control of gene expressions. Machine learning is becoming more and more widely used in …
[HTML][HTML] Omics-based investigations of breast cancer
Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …
[HTML][HTML] A panel of eight microRNAs is a good predictive parameter for triple-negative breast cancer relapse
Rationale: Triple-negative breast cancer (TNBC), which has the highest recurrence rate and
shortest survival time of all breast cancers, is in urgent need of a risk assessment method to …
shortest survival time of all breast cancers, is in urgent need of a risk assessment method to …
[HTML][HTML] Tear film microRNAs as potential biomarkers: A review
MicroRNAs are non-coding RNAs that serve as regulatory molecules in a variety of
pathways such as inflammation, metabolism, homeostasis, cell machinery, and …
pathways such as inflammation, metabolism, homeostasis, cell machinery, and …
miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense
M Pajic, D Froio, S Daly, L Doculara, E Millar… - Cancer research, 2018 - AACR
Radiotherapy is essential to the treatment of most solid tumors and acquired or innate
resistance to this therapeutic modality is a major clinical problem. Here we show that miR …
resistance to this therapeutic modality is a major clinical problem. Here we show that miR …
[HTML][HTML] A signature of four circulating microRNAs as potential biomarkers for diagnosing early-stage breast cancer
Breast cancer (BC) is the most predominant type of cancer among women. The aim of this
study is to find new biomarkers that can help in early detection of BC, especially for those …
study is to find new biomarkers that can help in early detection of BC, especially for those …
[HTML][HTML] miR-139-5p inhibits the epithelial-mesenchymal transition and enhances the chemotherapeutic sensitivity of colorectal cancer cells by downregulating BCL2
MicroRNAs (miRNAs) are important regulators involved in various cancers, including
colorectal cancer (CRC). The functions and mechanisms of the miRNAs involved in CRC …
colorectal cancer (CRC). The functions and mechanisms of the miRNAs involved in CRC …
Re‐thinking miRNA‐mRNA interactions: intertwining issues confound target discovery
N Cloonan - Bioessays, 2015 - Wiley Online Library
Despite a library full of literature on miRNA biology, core issues relating to miRNA target
detection, biological effect, and mode of action remain controversial. This essay proposes …
detection, biological effect, and mode of action remain controversial. This essay proposes …