In the whole life process, many factors including external and internal factors affect plant
growth and development. The morphogenesis, growth, and development of plants are …

Heritable variation in gene expression is common within and between species. This
variation arises from mutations that alter the form or function of molecular gene regulatory …

To enable low-cost, high-throughput generation of cistrome and epicistrome maps for any
organism, we developed DNA affinity purification sequencing (DAP-seq), a transcription …

Almost all polymerase II transcripts undergo alternative pre-mRNA splicing. Here, we review
the functions of alternative splicing events that have been experimentally determined. The …

Background Orthology analysis is an important part of data analysis in many areas of
bioinformatics such as comparative genomics and molecular phylogenetics. The ever …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

Alternative splicing of mRNA precursors provides an important means of genetic control and
is a crucial step in the expression of most genes. Alternative splicing markedly affects human …

Cytosolic detection of pathogen-derived nucleic acids is critical for the initiation of innate
immune defense against diverse bacterial, viral and eukaryotic pathogens. Conversely …

Human endogenous retrovirus subfamily H (HERVH) is a class of transposable elements
expressed preferentially in human embryonic stem cells (hESCs). Here, we report that the …

Transcription regulation networks control the expression of genes. The transcription
networks of well-studied microorganisms appear to be made up of a small set of recurring …