Atrial fibrillation (AF) is known to be the most common supraventricular arrhythmia affecting
up to 1% of the general population. Its prevalence exponentially increases with age and …

Pathogenic variants in the voltage-gated sodium channel gene family lead to early onset
epilepsies, neurodevelopmental disorders, skeletal muscle channelopathies, peripheral …

Mutations in Nav1. 4 and Nav1. 5 α-subunits have been associated with muscular and
cardiac channelopathies, respectively. Despite intense research on the structure and …

Diabetic peripheral neuropathy (DPN) is a common disabling complication of diabetes.
Almost half of the patients with DPN develop neuropathic pain (NeuP) for which current …

Aims SCN5A mutations are associated with various cardiac phenotypes, including long QT
syndrome type 3 (LQT3), Brugada syndrome (BrS), and cardiac conduction disease (CCD) …

Introduction Strong evidence shows that exercise is effective to improve fall risk factors
among older people. However, older people's participation and adherence to exercise …

Atrial fibrillation (AF) is the most frequent arrhythmogenic disease in humans, ranging from
2% in the general population and rising up to 10-12% in 80+ years. Genetic analyses of AF …

We present a term newborn with atrial arrhythmia on the first day of life (DOL). An
echocardiogram showed normal structure and normal function; laboratory testing showed …

Atrial fibrillation (AF) is the most frequent arrhythmogenic syndrome in humans. With an
estimate incidence of 1%-2% in the general population, AF raises up to almost 10%-12% in …

We describe a neonate born with complex arrhythmias that included concurrent atrial and
ventricular tachycardias. Genetic testing demonstrated a mutation in the TTN gene, which …