[HTML][HTML] The role of IL-1β and TNF-α in intervertebral disc degeneration
Y Wang, M Che, J Xin, Z Zheng, J Li, S Zhang - Biomedicine & …, 2020 - Elsevier
Low back pain (LBP), a prevalent and costly disease around the world, is predominantly
caused by intervertebral disc (IVD) degeneration (IDD). LBP also presents a substantial …
caused by intervertebral disc (IVD) degeneration (IDD). LBP also presents a substantial …
Discogenic low back pain: anatomy, pathophysiology and treatments of intervertebral disc degeneration
IL Mohd Isa, SL Teoh, NH Mohd Nor… - International journal of …, 2022 - mdpi.com
Intervertebral disc (IVD) degeneration is a major contributing factor for discogenic low back
pain (LBP), causing a significant global disability. The IVD consists of an inner core …
pain (LBP), causing a significant global disability. The IVD consists of an inner core …
Painful intervertebral disc degeneration and inflammation: from laboratory evidence to clinical interventions
Low back pain (LBP), as a leading cause of disability, is a common musculoskeletal disorder
that results in major social and economic burdens. Recent research has identified …
that results in major social and economic burdens. Recent research has identified …
Cell-based strategies for IVD repair: clinical progress and translational obstacles
ALA Binch, JC Fitzgerald, EA Growney… - Nature Reviews …, 2021 - nature.com
Intervertebral disc (IVD) degeneration is a major cause of low back pain, a prevalent and
chronic condition that has a striking effect on quality of life. Currently, no approved …
chronic condition that has a striking effect on quality of life. Currently, no approved …
Role of cytokines in intervertebral disc degeneration: pain and disc content
MV Risbud, IM Shapiro - Nature Reviews Rheumatology, 2014 - nature.com
Degeneration of the intervertebral discs (IVDs) is a major contributor to back, neck and
radicular pain. IVD degeneration is characterized by increases in levels of the …
radicular pain. IVD degeneration is characterized by increases in levels of the …
Biomaterials for intervertebral disc regeneration and repair
The intervertebral disc contributes to motion, weight bearing, and flexibility of the spine, but
is susceptible to damage and morphological changes that contribute to pathology with age …
is susceptible to damage and morphological changes that contribute to pathology with age …
The molecular basis of intervertebral disc degeneration
CK Kepler, RK Ponnappan, CA Tannoury, MV Risbud… - The Spine Journal, 2013 - Elsevier
BACKGROUND: Intervertebral disc (IVD) degeneration remains a clinically important
condition for which treatment is costly and relatively ineffective. The molecular basis of …
condition for which treatment is costly and relatively ineffective. The molecular basis of …
Lumbar degenerative disease part 1: anatomy and pathophysiology of intervertebral discogenic pain and radiofrequency ablation of basivertebral and sinuvertebral …
HS Kim, PH Wu, IT Jang - International journal of molecular sciences, 2020 - mdpi.com
Degenerative disc disease is a leading cause of chronic back pain in the aging population in
the world. Sinuvertebral nerve and basivertebral nerve are postulated to be associated with …
the world. Sinuvertebral nerve and basivertebral nerve are postulated to be associated with …
Intervertebral disc degeneration and how it leads to low back pain
The purpose of this review was to evaluate data generated by animal models of
intervertebral disc (IVD) degeneration published in the last decade and show how this has …
intervertebral disc (IVD) degeneration published in the last decade and show how this has …
Immuno-modulatory effects of intervertebral disc cells
P Bermudez-Lekerika, KB Crump… - Frontiers in cell and …, 2022 - frontiersin.org
Low back pain is a highly prevalent, chronic, and costly medical condition predominantly
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …