Diagnosis, prognosis and treatment of canine cutaneous and subcutaneous mast cell tumors

AB De Nardi, R dos Santos Horta, CE Fonseca-Alves… - Cells, 2022 - mdpi.com
Mast cell tumors (MCTs) are hematopoietic neoplasms composed of mast cells. It is highly
common in dogs and is extremely important in the veterinary oncology field. It represents the …

Mitosis domain generalization in histopathology images—the MIDOG challenge

M Aubreville, N Stathonikos, CA Bertram… - Medical Image …, 2023 - Elsevier
The density of mitotic figures (MF) within tumor tissue is known to be highly correlated with
tumor proliferation and thus is an important marker in tumor grading. Recognition of MF by …

A comprehensive multi-domain dataset for mitotic figure detection

M Aubreville, F Wilm, N Stathonikos, K Breininger… - Scientific data, 2023 - nature.com
The prognostic value of mitotic figures in tumor tissue is well-established for many tumor
types and automating this task is of high research interest. However, especially deep …

[HTML][HTML] SMDetector: Small mitotic detector in histopathology images using faster R-CNN with dilated convolutions in backbone model

HU Khan, B Raza, MH Shah, SM Usama… - … Signal Processing and …, 2023 - Elsevier
Breast cancer is one of the most common cancer types among women, and it is a deadly
disease caused by the uncontrolled proliferation of cells. Pathologists face a challenging …

Deep learning predicts patients outcome and mutations from digitized histology slides in gastrointestinal stromal tumor

Y Fu, M Karanian, R Perret, A Camara… - Npj Precision …, 2023 - nature.com
Risk assessment of gastrointestinal stromal tumor (GIST) according to the AFIP/Miettinen
classification and mutational profiling are major tools for patient management. However, the …

Feline soft tissue sarcomas: a review of the classification and histological grading, with comparison to human and canine

M Dobromylskyj - Animals, 2022 - mdpi.com
Simple Summary Soft tissue sarcomas are a common form of cancer arising in the skin and
connective tissues of domestic cats. Soft tissue sarcomas encompass a group of different …

Enhancing mitosis quantification and detection in meningiomas with computational digital pathology

H Gu, C Yang, I Al-Kharouf, S Magaki, N Lakis… - Acta Neuropathologica …, 2024 - Springer
Mitosis is a critical criterion for meningioma grading. However, pathologists' assessment of
mitoses is subject to significant inter-observer variation due to challenges in locating mitosis …

[HTML][HTML] Domain generalization across tumor types, laboratories, and species—Insights from the 2022 edition of the Mitosis Domain Generalization Challenge

M Aubreville, N Stathonikos, TA Donovan… - Medical Image …, 2024 - Elsevier
Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient
outcome assessment. This task is challenging for algorithms and human experts alike, with …

Automated diagnosis of 7 canine skin tumors using machine learning on H&E-stained whole slide images

M Fragoso-Garcia, F Wilm, CA Bertram… - Veterinary …, 2023 - journals.sagepub.com
Microscopic evaluation of hematoxylin and eosin-stained slides is still the diagnostic gold
standard for a variety of diseases, including neoplasms. Nevertheless, intra-and interrater …

Artificial intelligence to predict the BRAF V595E mutation in canine urinary bladder urothelial carcinomas

L Küchler, C Posthaus, K Jäger, F Guscetti… - Animals, 2023 - mdpi.com
Simple Summary In canine urothelial carcinoma, the BRAF gene is frequently mutated
(V595E). To detect this mutation, urine or tissue samples are currently tested by PCR …