[HTML][HTML] Protective roles of thymoquinone nanoformulations: potential nanonutraceuticals in human diseases

AH El-Far, SK Al Jaouni, W Li, SA Mousa - Nutrients, 2018 - mdpi.com
The focus on nanotechnology for improved bioavailability and drug delivery is of increasing
importance for control of different human diseases. Therefore, numerous nanoformulations …

[HTML][HTML] Mechanism of the antidiabetic action of Nigella sativa and Thymoquinone: a review

A Shaukat, A Zaidi, H Anwar, N Kizilbash - Frontiers in Nutrition, 2023 - frontiersin.org
Introduction Long used in traditional medicine, Nigella sativa (NS; Ranunculaceae) has
shown significant efficacy as an adjuvant therapy for diabetes mellitus (DM) management by …

[HTML][HTML] Self-nanoemulsifying drug delivery system (SNEDDS) mediated improved oral bioavailability of thymoquinone: optimization, characterization …

C Rathore, C Hemrajani, AK Sharma, PK Gupta… - Drug Delivery and …, 2023 - Springer
Thymoquinone (TQ) is an antioxidant, anti-inflammatory, and hepatoprotective compound
obtained from the black seed oil of Nigella sativa. However, high hydrophobicity, instability …

[HTML][HTML] Preparation of liposomal formulations for ocular delivery of thymoquinone: in vitro evaluation in HCEC-2 e HConEC cells

E Landucci, F Bonomolo, C De Stefani, C Mazzantini… - Pharmaceutics, 2021 - mdpi.com
Thymoquinone (TQ) is the main constituent of Nigella sativa L. essential oil. In vitro studies
have shown its protective effect against H2O2-induced oxidative stress in human retinal …

Nanocarriers: more than tour de force for thymoquinone

C Rathore, MJ Rathbone, DK Chellappan… - Expert Opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction: Thymoquinone (TQ), 2-isopropyl-5-methylbenzo-1, 4-quinone, the
main active constituent of Nigella sativa (NS) plant, has been proven to be of great …

[HTML][HTML] The effect of natural products on inflammatory cytokines production and secretion

M Barakat, NK Syed, E Hasen, SB Abdulrazzaq… - Phytomedicine Plus, 2023 - Elsevier
Background: The human body is regulated by the controlled production and secretion of
thousands of chemicals, including polypeptides called cytokines. Cytokines play crucial …

Ethosomes: Novel Vesicular Carriers for Effective Transdermal Delivery of Natural Therapeutics

S Bhatia, V Singh, M Singh, D Singh… - Letters in Drug …, 2024 - ingentaconnect.com
The topical delivery, being the most reliable route for drug administration, offers multiple
advantages. The conventional topical dosage forms deliver a relatively higher amount of …

[HTML][HTML] Plant-Based Biostimulants for Seeds in the Context of Circular Economy and Sustainability

H Wazeer, S Shridhar Gaonkar, E Doria, A Pagano… - Plants, 2024 - mdpi.com
Plant-based biostimulants (PBs), agents rich in bioactive compounds, are emerging as key
players able to sustainably improve plant growth and crop productivity to address food …

Whole-cell bioconversion for producing thymoquinone by engineered Saccharomyces cerevisiae

E Kim, M Kim, MK Oh - Enzyme and Microbial Technology, 2024 - Elsevier
Thymoquinone, extracted from the black seeds of Nigella sativa, is a natural substance with
highly beneficial effects against various human diseases. In this study, we aimed to construct …

[HTML][HTML] Nephroprotective effects of ethanolic root extract of Azima tetracantha lam in adenine-induced chronic kidney failure in Wistar rats

R Arunachalam, VGR Konda, M Eerike… - Indian Journal of …, 2021 - journals.lww.com
Nephroprotective effects of ethanolic root extract of Azima... : Indian Journal of
Pharmacology Nephroprotective effects of ethanolic root extract of Azima tetracantha lam in …