Genetics of human primary hypertension: focus on hormonal mechanisms

W Manosroi, GH Williams - Endocrine reviews, 2019 - academic.oup.com
Increasingly, primary hypertension is being considered a syndrome and not a disease, with
the individual causes (diseases) having a common sign—an elevated blood pressure. To …

[HTML][HTML] Альдостеронсинтаза, полиморфизмее гена CYP11B2 при артериальной гипертензии и ассоциированныхс нею кардиоваскулярных заболеваниях …

ДК Милославский, СН Коваль… - Артериальная …, 2017 - cyberleninka.ru
В обзоре представлены данные зарубежной и отечественной литературы о
патогенетической роли альдостерона, уровней альдостеронсинтазы и …

[HTML][HTML] Effect of ACE, ACE2 and CYP11B2 gene polymorphisms and noise on essential hypertension among steelworkers in China: a case–control study

X Zhang, Y Wang, Y Zheng, J Yuan, J Tong, J Xu… - BMC Medical …, 2022 - Springer
Background Previous studies on the relationship between ACE I/D, ACE2 G8790A and
CYP11B2-344T/C gene polymorphisms and essential hypertension (EH) were inconsistent …

Aldosterone and Hypertension

WW Parksook, GH Williams - Hypertension, 2024 - Elsevier
Hypertension is one of the leading causes of death worldwide and the primary risk factor for
ischemic and hemorrhagic strokes and coronary artery disease. The role of aldosterone and …

[HTML][HTML] A novel haplotype of low-frequency variants in the aldosterone synthase gene among northern Han Chinese with essential hypertension

H Zhang, X Li, L Zhou, K Zhang, Q Zhang, J Li… - Medicine, 2017 - journals.lww.com
Low-frequency variants showed that there is more power to detect risk variants than to detect
protective variants in complex diseases. Aldosterone plays an important role in the renin …

[HTML][HTML] Вазоактивные гены как молекулярно-генетические предикторы тяжелой преэклампсии

ТЕ Белокриницкая, НИ Фролова… - Гинекология, 2019 - cyberleninka.ru
Цель. Проанализировать частоту встречаемости полиморфизмов и комбинаций генов
AGT-704T> C, AGT-521C> T, AGTR1-1166A> C, AGTR2-1675G> A, еNO3-786T> C …

[HTML][HTML] ГЕНЕТИЧЕСКИЕ ПРЕДИКТОРЫ РАННЕЙ И ПОЗДНЕЙ ФОРМ ПРЕЭКЛАМПСИИ. ПАТОГНЕТИЧЕСКИЕ ПОДХОДЫК ЛЕЧЕНИЮ ПРЕЭКЛАПМСИИ

ЛД Белоцерковцева, ДП Телицын… - Вестник СурГУ …, 2019 - cyberleninka.ru
Цель-провести поиск литературы о генетических предикторах ранней и поздней
преэклампсии с позиции доказательной медицины и об определении патогенетических …

Association of combined− 344T/C and K173R polymorphisms in aldosterone synthase gene with type 2 diabetes mellitus in the Moroccan population.

Y Nouhi, FZ Aboubakr, O El Brini… - Romanian Journal of …, 2024 - sciendo.com
Background: Aldosterone synthase (CYP11B2) is crucial for aldosterone production, and
variations in its gene may influence type 2 diabetes mellitus (T2DM) development. This …

Aldosterone synthase gene (CYP11B2) polymorphisms and enhanced cardiovascular risk

MTA Ghafar - The recent topics in genetic polymorphisms, 2019 - books.google.com
Aldosterone, the principal human mineralocorticoid, acts mainly for sodium reabsorption
with potassium and hydrogen excretion. The adrenal cortex is the main site of aldosterone …

CYP11B2 基因-344C/T 多态与云南双河乡彝族人群原发性高血压的相关性.

彭红瑜, 范志祥, 张延洁, 舒芯… - Journal of Kunming …, 2021 - search.ebscohost.com
目的研究CYP11B2 基因-344C/T 多态与云南省晋宁县双河乡彝族人群原发性高血压的相关性.
方法采集308 例云南省晋宁县双河乡彝族居民外周血, 包括132 例原发性高血压患者(EH 组) …