The biosynthesis, signaling, and neurological functions of bile acids

Y Kiriyama, H Nochi - Biomolecules, 2019 - mdpi.com
Bile acids (BA) are amphipathic steroid acids synthesized from cholesterol in the liver. They
act as detergents to expedite the digestion and absorption of dietary lipids and lipophilic …

Herbal remedies and their possible effect on the GABAergic system and sleep

O Bruni, L Ferini-Strambi, E Giacomoni, P Pellegrino - Nutrients, 2021 - mdpi.com
Sleep is an essential component of physical and emotional well-being, and lack, or
disruption, of sleep due to insomnia is a highly prevalent problem. The interest in …

Physiological role of bile acids modified by the gut microbiome

Y Kiriyama, H Nochi - Microorganisms, 2021 - mdpi.com
Bile acids (BAs) are produced from cholesterol in the liver and are termed primary BAs.
Primary BAs are conjugated with glycine and taurine in the liver and then released into the …

Bile acids as key modulators of the brain-gut-microbiota axis in Alzheimer's disease

A Mulak - Journal of Alzheimer's Disease, 2021 - content.iospress.com
Recently, the concept of the brain-gut-microbiota (BGM) axis disturbances in the
pathogenesis of Alzheimer's disease (AD) has been receiving growing attention. At the …

Roles of bile acids signaling in neuromodulation under physiological and pathological conditions

C Xing, X Huang, D Wang, D Yu, S Hou, H Cui, L Song - Cell & bioscience, 2023 - Springer
Bile acids (BA) are important physiological molecules not only mediating nutrients
absorption and metabolism in peripheral tissues, but exerting neuromodulation effect in the …

[HTML][HTML] Anxiolytic properties of Cymbopogon citratus (DC.) stapf extract, essential oil and its constituents in zebrafish (Danio rerio)

ACM Hacke, E Miyoshi, JA Marques… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Cymbopogon citratus (DC.) Stapf (Poaceae) leaves is
often consumed as infusion in folk medicine due to its therapeutic properties. This plant is …

Essential Oil from the Leaves of Chromolaena odorata, and Sesquiterpene Caryophyllene Oxide Induce Sedative Activity in Mice

G Dougnon, M Ito - Pharmaceuticals, 2021 - mdpi.com
Chromolaena odorata (L.) RM King & H. Rob. essential oil (COEO) was investigated for its
sedative activity in mice. The results showed that COEO significantly reduced mice …

Functional alternatives to alcohol

DJ Nutt, RJ Tyacke, M Spriggs, V Jacoby, AD Borthwick… - Nutrients, 2022 - mdpi.com
The consumption of alcohol is associated with well-known health harms and many
governments worldwide are actively engaged in devising approaches to reduce them. To …

Multiple myeloma inhibitory activity of plant natural products

K Jöhrer, SS Ҫiҫek - Cancers, 2021 - mdpi.com
Simple Summary Multiple myeloma is the second most common hematological cancer and
is still incurable. Although enhanced understanding of the disease background and the …

Natural allosteric modulators and their biological targets: molecular signatures and mechanisms

M Bruder, G Polo, DBB Trivella - Natural product reports, 2020 - pubs.rsc.org
Covering: 2008 to 2018 Over the last decade more than two hundred single natural products
were confirmed as natural allosteric modulators (alloNPs) of proteins. The compounds are …