In this state-of-the-art review, we highlight the major advances over the last 5 years in
neonatal acute kidney injury (AKI). Large multicenter studies reveal that neonatal AKI is …

As a result of preterm birth, immature kidneys are exposed to interventions in the NICU that
promote survival, but are nephrotoxic. Furthermore, the duration of renal development may …

Pediatric acute kidney injury (AKI) is a frequently missed complication. AKI has a significant
impact on both short-and long-term outcomes in children. Within the last decade, there have …

The homeostasis and health of an organism depend on the coordinated interaction of
specialized organs, which is regulated by interorgan communication networks of circulating …

Background Neonates admitted in the neonatal intensive care unit are vulnerable to acute
kidney injury leading to worse outcomes. It is important to identify “at-risk” neonates for early …

Acute kidney injury (AKI) occurs in nearly 30% of sick neonates. Chronic kidney disease
(CKD) can be detected in certain populations of sick neonates as early as 2 years. AKI is …

Background Acute kidney injury (AKI) is common in sick neonates and associated with poor
pulmonary outcomes, however, the mechanisms responsible remain unknown. We present …

In 2013, literature about the epidemiology of neonatal acute kidney injury (AKI) was limited
to primarily retrospective, single center studies that suggested that AKI was common and …

Numerous studies have shown that the M2 polarization of alveolar macrophages (AM) plays
a protective role in acute lung injury (ALI). Mesenchymal stem cells (MSCs) secreted …

Over the past two decades, our understanding of the impact of acute kidney injury, disorders
of fluid balance, and their interplay have increased significantly. In recent years, the …