Type 2 diabetes mellitus (T2DM) is a multifactorial non-communicable disease that is
characterized by insulin resistance and chronic sub-clinical inflammation. Among the …

The escalating prevalence of individuals becoming overweight and obese is a rapidly rising
global health problem, placing an enormous burden on health and economic systems …

Inflammasome activation of the nucleotide-binding domain, leucine-rich–containing family,
and pyrin domain–containing-3 (NLRP3) has been observed to be involved in the …

Hyperglycemia associated with prediabetes (PD) alters NLRP3 inflammasome activity and
related interleukins, yet no study has evaluated the expression of the NLRP3 inflammasome …

Vitamin D (VD) deficiency has been associated with inflammation and dysregulation of the
immune system. The NLRP3 inflammasome, a critical immune response component, plays a …

This study aimed to assess several indicators of adiposity and their effectiveness in
predicting metabolic syndrome (MetS) and identify their cut-off values among general Saudi …

Background Insulin resistance (IR) is considered the main driver of obesity related metabolic
complications, and is related to oxidative stress and inflammation, which in turn promote …

Conclusion In conclusion, the increased prevalence of metabolic illnesses necessitates the
development of novel therapeutic and preventative treatments, taking into account that each …